Successfully resected hepatoblastoma in a young adult with chronic hepatitis B: Report of a case

M. Inagaki, Takahito Yagi, N. Urushihara, Y. Shima, H. Sadamori, N. Takakura, N. Tanaka, M. Oda

Research output: Contribution to journalArticle

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Abstract

Hepatoblastoma usually occurs in children, but a few cases have also been reported in adults. We report the unusual case of hepatoblastoma in an 18-year-old adult with chronic hepatitis B. He visited a local hospital with right upper abdominal pain. Abdominal ultrasound showed a large mass in the right lobe of his liver. He was referred to our hospital and admitted for further examination. At admission, liver function tests gave slightly elevated results (aspartate aminotransferase (AST) 103 IU/I, alanine aminotransferase (ALT) 63 IU/I). A test for hepatitis virus revealed that he was a hepatitis B surface antigen (HBsAg) carrier and had experienced seroconversion. His alpha-fetoprotein (AFP) was elevated to 1 548 000 IU/ml. Abdominal ultrasound showed a 109 × 96 × 80-mm mass with mosaic pattern in the right lobe of the liver and right portal vein thrombus. Abdominal computed tomography (CT) demonstrated a large low-density mass occupying the right lobe, with some high-density parts that showed calcification. From these results, we diagnosed hepatoblastoma in a young adult. A right lobectomy was performed. Pathological examination showed a highly differentiated hepatoblastoma. Adjuvant chemotherapy was performed with cisplatin and pirarubicin. The patient has been well and free of recurrence for 12 months, and his AFP level remains almost normal.

Original languageEnglish
Pages (from-to)981-984
Number of pages4
JournalEuropean Journal of Gastroenterology and Hepatology
Volume13
Issue number8
DOIs
Publication statusPublished - 2001

Fingerprint

Hepatoblastoma
Chronic Hepatitis B
Young Adult
alpha-Fetoproteins
Hepatitis A virus
Liver
Liver Function Tests
Adjuvant Chemotherapy
Hepatitis B Surface Antigens
Aspartate Aminotransferases
Portal Vein
Alanine Transaminase
Abdominal Pain
Cisplatin
Thrombosis
Tomography
Recurrence

Keywords

  • Adult
  • Alpha-fetoprotein
  • Chemotherapy
  • Hepatoblastoma
  • Surgical operation

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Successfully resected hepatoblastoma in a young adult with chronic hepatitis B : Report of a case. / Inagaki, M.; Yagi, Takahito; Urushihara, N.; Shima, Y.; Sadamori, H.; Takakura, N.; Tanaka, N.; Oda, M.

In: European Journal of Gastroenterology and Hepatology, Vol. 13, No. 8, 2001, p. 981-984.

Research output: Contribution to journalArticle

Inagaki, M. ; Yagi, Takahito ; Urushihara, N. ; Shima, Y. ; Sadamori, H. ; Takakura, N. ; Tanaka, N. ; Oda, M. / Successfully resected hepatoblastoma in a young adult with chronic hepatitis B : Report of a case. In: European Journal of Gastroenterology and Hepatology. 2001 ; Vol. 13, No. 8. pp. 981-984.
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