Successful treatment with glucocorticoid for secondary Fanconi syndrome caused by sarcoidosis

Research output: Contribution to journalArticle

Abstract

A 77-year-old female with renal dysfunction, hypercalcemia, and hypercalciuria was presented. Systemic investigations including renal biopsy showed that the patient had Fanconi syndrome secondary to renal sarcoidosis. Treatment with 25 mg per day of prednisolone was initiated and her condition improved. Complication of Fanconi syndrome in patients with sarcoidosis is extremely rare. Although the pathological mechanism is still unknown, corticosteroid therapy was effective for ameliorating proteinuria, glycosuria, hypercalciuria, and aminoaciduria.

Original languageEnglish
JournalModern Rheumatology
DOIs
Publication statusAccepted/In press - Jul 30 2015

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Fanconi Syndrome
Sarcoidosis
Glucocorticoids
Hypercalciuria
Kidney
Glycosuria
Hypercalcemia
Prednisolone
Proteinuria
Adrenal Cortex Hormones
Therapeutics
Biopsy

Keywords

  • Corticosteroid
  • Fanconi syndrome
  • Hypercalcemia
  • Sarcoidosis

ASJC Scopus subject areas

  • Rheumatology

Cite this

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title = "Successful treatment with glucocorticoid for secondary Fanconi syndrome caused by sarcoidosis",
abstract = "A 77-year-old female with renal dysfunction, hypercalcemia, and hypercalciuria was presented. Systemic investigations including renal biopsy showed that the patient had Fanconi syndrome secondary to renal sarcoidosis. Treatment with 25 mg per day of prednisolone was initiated and her condition improved. Complication of Fanconi syndrome in patients with sarcoidosis is extremely rare. Although the pathological mechanism is still unknown, corticosteroid therapy was effective for ameliorating proteinuria, glycosuria, hypercalciuria, and aminoaciduria.",
keywords = "Corticosteroid, Fanconi syndrome, Hypercalcemia, Sarcoidosis",
author = "Daisuke Omura and Hideharu Hagiya and Yoshihisa Hanayama and Kou Hasegawa and Hiroshi Morinaga and Atsue Kikuta and Hitomi Kataoka and Fumio Otsuka",
year = "2015",
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AU - Omura, Daisuke

AU - Hagiya, Hideharu

AU - Hanayama, Yoshihisa

AU - Hasegawa, Kou

AU - Morinaga, Hiroshi

AU - Kikuta, Atsue

AU - Kataoka, Hitomi

AU - Otsuka, Fumio

PY - 2015/7/30

Y1 - 2015/7/30

N2 - A 77-year-old female with renal dysfunction, hypercalcemia, and hypercalciuria was presented. Systemic investigations including renal biopsy showed that the patient had Fanconi syndrome secondary to renal sarcoidosis. Treatment with 25 mg per day of prednisolone was initiated and her condition improved. Complication of Fanconi syndrome in patients with sarcoidosis is extremely rare. Although the pathological mechanism is still unknown, corticosteroid therapy was effective for ameliorating proteinuria, glycosuria, hypercalciuria, and aminoaciduria.

AB - A 77-year-old female with renal dysfunction, hypercalcemia, and hypercalciuria was presented. Systemic investigations including renal biopsy showed that the patient had Fanconi syndrome secondary to renal sarcoidosis. Treatment with 25 mg per day of prednisolone was initiated and her condition improved. Complication of Fanconi syndrome in patients with sarcoidosis is extremely rare. Although the pathological mechanism is still unknown, corticosteroid therapy was effective for ameliorating proteinuria, glycosuria, hypercalciuria, and aminoaciduria.

KW - Corticosteroid

KW - Fanconi syndrome

KW - Hypercalcemia

KW - Sarcoidosis

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