Successful treatment of two patients with advanced gastric cancer by neoadjuvant chemotherapy with EAP regimens

T. Matsumura, T. Ohnoshi, H. Ueoka, Katsuyuki Kiura, Masahiro Tabata, K. Genba, M. Chikamori, S. Ikubo, K. Matsuo, I. Kimura

Research output: Contribution to journalArticle

Abstract

Two patients with unresectable gastric cancer accompanied with multiple liver metastases were treated with a 3-drug combination consisting of etoposide, adriamycin, and cisplatin (EAP) as neoadjuvant chemotherapy. After confirmation of maximal response to EAP, both patients received surgical resection of the primary tumor and infusion of cisplatin and 5-FU into hepatic artery, and they survived 15.0 and 15.8 months, respectively. These results indicate that neoadjuvant chemotherapy with EAP regimen is useful in the treatment of advanced gastric cancer.

Original languageEnglish
Pages (from-to)261-264
Number of pages4
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume21
Issue number2
Publication statusPublished - 1994

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Cisplatin
Stomach Neoplasms
Drug Therapy
Hepatic Artery
Etoposide
Drug Combinations
Fluorouracil
Doxorubicin
Neoplasm Metastasis
Liver
Therapeutics
Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Pharmacology

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Successful treatment of two patients with advanced gastric cancer by neoadjuvant chemotherapy with EAP regimens. / Matsumura, T.; Ohnoshi, T.; Ueoka, H.; Kiura, Katsuyuki; Tabata, Masahiro; Genba, K.; Chikamori, M.; Ikubo, S.; Matsuo, K.; Kimura, I.

In: Gan to kagaku ryoho. Cancer & chemotherapy, Vol. 21, No. 2, 1994, p. 261-264.

Research output: Contribution to journalArticle

Matsumura, T, Ohnoshi, T, Ueoka, H, Kiura, K, Tabata, M, Genba, K, Chikamori, M, Ikubo, S, Matsuo, K & Kimura, I 1994, 'Successful treatment of two patients with advanced gastric cancer by neoadjuvant chemotherapy with EAP regimens', Gan to kagaku ryoho. Cancer & chemotherapy, vol. 21, no. 2, pp. 261-264.
Matsumura, T. ; Ohnoshi, T. ; Ueoka, H. ; Kiura, Katsuyuki ; Tabata, Masahiro ; Genba, K. ; Chikamori, M. ; Ikubo, S. ; Matsuo, K. ; Kimura, I. / Successful treatment of two patients with advanced gastric cancer by neoadjuvant chemotherapy with EAP regimens. In: Gan to kagaku ryoho. Cancer & chemotherapy. 1994 ; Vol. 21, No. 2. pp. 261-264.
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AU - Tabata, Masahiro

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AU - Chikamori, M.

AU - Ikubo, S.

AU - Matsuo, K.

AU - Kimura, I.

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