Successful treatment of sepsis caused by Staphylococcus lugdunensis in an adult with 22q11.2 deletion syndrome

Shoji Hirasaki, Kazutoshi Murakami, Takaaki Mizushima, Kazuyoshi Ohmori, Seiko Fujita, Yoshihisa Hanayama, Tatsuya Kanamori, Ryo Yokota, Hirotaka Ebara, Nobuchika Kusano, Chieko Kudo, Tomoko Yamaguchi, Teiji Akagi, Norio Koide

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A 27-year-old woman visited our hospital because of high fever. She had been diagnosed as 22q11.2 deletion syndrome (22q11.2DS) due to her cardiac history (tetralogy of Fallot), thymic hypoplasia and 22q11.2 deletion. She had a normal CD4/CD8 ratio, a slightly decreased lymphocyte count and normal serum immunoglobulin levels. Blood cultures were positive for Staphylococcus lugdunensis (S. lugdunensis). Infection route of S. lugdunensis in this case was unclear. The patient was successfully treated with several intravenous antibiotics. Infection should be considered when managing patients with 22q.11.2DS. regardless of whether their immune system is impaired.

Original languageEnglish
Pages (from-to)377-380
Number of pages4
JournalInternal Medicine
Volume51
Issue number4
DOIs
Publication statusPublished - 2012

Fingerprint

Staphylococcus lugdunensis
DiGeorge Syndrome
Sepsis
CD4-CD8 Ratio
Tetralogy of Fallot
Lymphocyte Count
Infection
Immunoglobulins
Immune System
Fever
History
Anti-Bacterial Agents
Therapeutics
Serum

Keywords

  • Blood culture
  • Dental disease
  • Staphylococcal infection
  • Tetralogy of fallot

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Successful treatment of sepsis caused by Staphylococcus lugdunensis in an adult with 22q11.2 deletion syndrome. / Hirasaki, Shoji; Murakami, Kazutoshi; Mizushima, Takaaki; Ohmori, Kazuyoshi; Fujita, Seiko; Hanayama, Yoshihisa; Kanamori, Tatsuya; Yokota, Ryo; Ebara, Hirotaka; Kusano, Nobuchika; Kudo, Chieko; Yamaguchi, Tomoko; Akagi, Teiji; Koide, Norio.

In: Internal Medicine, Vol. 51, No. 4, 2012, p. 377-380.

Research output: Contribution to journalArticle

Hirasaki, S, Murakami, K, Mizushima, T, Ohmori, K, Fujita, S, Hanayama, Y, Kanamori, T, Yokota, R, Ebara, H, Kusano, N, Kudo, C, Yamaguchi, T, Akagi, T & Koide, N 2012, 'Successful treatment of sepsis caused by Staphylococcus lugdunensis in an adult with 22q11.2 deletion syndrome', Internal Medicine, vol. 51, no. 4, pp. 377-380. https://doi.org/10.2169/internalmedicine.51.6257
Hirasaki, Shoji ; Murakami, Kazutoshi ; Mizushima, Takaaki ; Ohmori, Kazuyoshi ; Fujita, Seiko ; Hanayama, Yoshihisa ; Kanamori, Tatsuya ; Yokota, Ryo ; Ebara, Hirotaka ; Kusano, Nobuchika ; Kudo, Chieko ; Yamaguchi, Tomoko ; Akagi, Teiji ; Koide, Norio. / Successful treatment of sepsis caused by Staphylococcus lugdunensis in an adult with 22q11.2 deletion syndrome. In: Internal Medicine. 2012 ; Vol. 51, No. 4. pp. 377-380.
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