Successful treatment of limited disease-small cell lung cancer with multimodality treatment consisting of concurrent chemoradiotherapy, high-dose chemotherapy with autologous peripheral blood stem cell transplantation and surgical resection

Katsuyuki Hotta, Hiroshi Ueoka, Katsuyuki Kiura, Masahiro Tabata, Eisei Kondoh, Yoshihiko Segawa, Hiroshi Date, Nobuyoshi Shimizu, Tadashi Yoshino, Mine Harada, Mitsune Tanimoto

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A 65-year-old man with limited disease-small cell lung cancer was treated with concurrent chemoradiotherapy which resulted in a partial response. He further received high-dose chemotherapy with autologous peripheral blood stem cell transplantation. Development of non-small cell carcinoma was, however, suspected at a site of the residual nodule in cytological examination using bronchoscopy. He then underwent lobectomy, which revealed that the nodule was composed of necrotic tissue. He has been alive without recurrence for seven years. This multimodality treatment appeared to be effective for this patient. However, further investigation is necessary to clarify the role of multimodality treatment.

Original languageEnglish
Pages (from-to)1223-1227
Number of pages5
JournalInternal Medicine
Volume42
Issue number12
Publication statusPublished - Dec 2003

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Peripheral Blood Stem Cell Transplantation
Small Cell Lung Carcinoma
Chemoradiotherapy
Drug Therapy
Bronchoscopy
Carcinoma
Recurrence
Therapeutics

Keywords

  • Autologous peripheral blood stem cell transplantation
  • Chemoradiotherapy
  • High-dose chemotherapy
  • Small cell lung cancer
  • Surgery

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Successful treatment of limited disease-small cell lung cancer with multimodality treatment consisting of concurrent chemoradiotherapy, high-dose chemotherapy with autologous peripheral blood stem cell transplantation and surgical resection. / Hotta, Katsuyuki; Ueoka, Hiroshi; Kiura, Katsuyuki; Tabata, Masahiro; Kondoh, Eisei; Segawa, Yoshihiko; Date, Hiroshi; Shimizu, Nobuyoshi; Yoshino, Tadashi; Harada, Mine; Tanimoto, Mitsune.

In: Internal Medicine, Vol. 42, No. 12, 12.2003, p. 1223-1227.

Research output: Contribution to journalArticle

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AU - Tabata, Masahiro

AU - Kondoh, Eisei

AU - Segawa, Yoshihiko

AU - Date, Hiroshi

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