Successful treatment of breakthrough trichosporon asahii fungemia with voriconazole in a patient with acute myeloid leukemia

Noboru Asada, Hidetaka Uryu, Mihoko Koseki, Masami Takeuchi, Masaru Komatsu, Kosei Matsue

Research output: Contribution to journalArticle

50 Citations (Scopus)


We describe a 55-year-old man with acute myelogenous leukemia who developed breakthrough Trichosporon asahii fungemia during 5 days of micafungin treatment. Although the patients clinical condition improved considerably after the start of voriconazole treatment, blood culture Results remained positive for T. asahii for 3 days, and fever persisted for 7 days thereafter. The patient achieved complete hematological remission, and he received successful consolidation chemotherapy without developing Trichosporon infection with the prophylactic use of voriconazole therapy. This case report illustrates that voriconazole may be useful in the treatment of disseminated T. asahii infection in neutropenic patients.

Original languageEnglish
Pages (from-to)e39-e41
JournalClinical Infectious Diseases
Issue number4
Publication statusPublished - Aug 15 2006


ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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