Successful resection of rectal carcinoma in an Evans' syndrome patient followed by predonisolone and high-dose immunoglobulin: Report of a case

Atsunori Nakao, Hiromi Iwagaki, Kenji Notohara, Yushinori Morimoto, Norifumi Ariki, Taiichiro Kanagawa, Hiroshi Isozaki, Noriaki Tanaka

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A 69-year-old woman was admitted to our hospital because of anal bleeding and fatigue. The patient was previously diagnosed as having Evans' syndrome on the basis of hematological examination and had been treated with predonisolone for 8 years. On admission, severe anemia and thrombocytopenia were noted. Colonoscopy and Barium enema studies demonstrated an irregular tumor with hemorrhagic ulceration in the rectum, which was histopathologically confirmed as an adenocarcinoma. After red blood cells and platelets were transfused, and the patient was treated with high-dose gammaglobulin, predonisolone, and camostat mesylate, the platelet count gradually increased and hemolysis was well controlled. The patient then underwent Hartmann's operation and splenectomy without any postoperative complications. Predonisolone and high-dose immunoglobulin therapy in a rectal cancer burdened patient with Evans' syndrome is considered useful in combination with surgical treatment. This is the first case report of rectal carcinoma resection in a patient with Evans' syndrome.

Original languageEnglish
Pages (from-to)253-257
Number of pages5
JournalActa medica Okayama
Volume55
Issue number4
Publication statusPublished - Dec 1 2001

Keywords

  • Autoimmune hemolytic anemia
  • Immune thrombocytopenia
  • Surgical treatment

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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    Nakao, A., Iwagaki, H., Notohara, K., Morimoto, Y., Ariki, N., Kanagawa, T., Isozaki, H., & Tanaka, N. (2001). Successful resection of rectal carcinoma in an Evans' syndrome patient followed by predonisolone and high-dose immunoglobulin: Report of a case. Acta medica Okayama, 55(4), 253-257.