Abstract
The Mizoroki-Heck type reaction of methyl(phenyl)(3,3,3- trifluoropropyl)silanol (1a) with ethyl acrylate in the presence of Pd(OAc)2 (10 mol%) and Cu(OAc)2/LiOAc gave ethyl cinnamate in 70% yield. The palladium-catalyzed cross-coupling of 1a with 4-iodomethoxybenzene in the presence of Ag2O also afforded 4-methoxybiphenyl in 51% yield.
| Original language | English |
|---|---|
| Pages (from-to) | 749-750 |
| Number of pages | 2 |
| Journal | Bulletin of the Chemical Society of Japan |
| Volume | 73 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Mar 2000 |
ASJC Scopus subject areas
- Chemistry(all)
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Hirabayashi, K., Kondo, T., Toriyama, F., Nishihara, Y., & Mori, A. (2000). Substituent effect of 3,3,3-trifluoropropyl group on organic silanols. Palladium-mediated Mizoroki-Heck type and cross-coupling reactions. Bulletin of the Chemical Society of Japan, 73(3), 749-750. https://doi.org/10.1246/bcsj.73.749