Study on effects of thoron and thermal treatment for aging-related diseases in humans

Y. Aoyama, Takahiro Kataoka, Sh Nakagawa, A. Sakoda, Y. Ishimori, Fumihiro Mitsunobu, Kiyonori Yamaoka

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: The aim of this study was to analyze the effects of thoron and thermal treatment for aging-related diseases in humans. Materials and Methods: All subjects inhaled thoron with a high concentration (about 4900 Bq/m3) for 2 weeks. Blood pressures were measured and blood samples were collected after each treatment 1, 2 and 3 weeks after the first treatment. Results: The α-atrial natriuretic peptide level of the rheumatoid arthritis group was increased and the blood pressure was significantly decreased. Superoxide dismutase activity of rheumatoid arthritis group was significantly increased by treatment. In addition, thoron and thermal treatment significantly enhanced the concanavalin A-induced mitogen response and increased the level of CD4-positive cells; it decreased the level of CD8-positive cells. The results suggest that thoron and thermal treatment activates antioxidative function. Furthermore, these findings suggest that thoron and thermal treatment prevents diabetic ketoacidosis and contributes to the prevention of aging-related diseases. Conclusion: Thoron and thermal therapy may be part of the mechanism for the alleviation of diabetes mellitus and rheumatoid arthritis.

Original languageEnglish
Pages (from-to)221-229
Number of pages9
JournalIranian Journal of Radiation Research
Volume9
Issue number4
Publication statusPublished - 2012

Fingerprint

Hot Temperature
Rheumatoid Arthritis
Blood Pressure
Diabetic Ketoacidosis
Atrial Natriuretic Factor
Concanavalin A
Mitogens
Superoxide Dismutase
Diabetes Mellitus
Therapeutics

Keywords

  • Antioxidant function
  • Diabetes mellitus
  • Health effect
  • Rheumatoid arthritis
  • Thoron and thermal treatment

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Study on effects of thoron and thermal treatment for aging-related diseases in humans. / Aoyama, Y.; Kataoka, Takahiro; Nakagawa, Sh; Sakoda, A.; Ishimori, Y.; Mitsunobu, Fumihiro; Yamaoka, Kiyonori.

In: Iranian Journal of Radiation Research, Vol. 9, No. 4, 2012, p. 221-229.

Research output: Contribution to journalArticle

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AU - Mitsunobu, Fumihiro

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