Structures of isorugosin E and hirtellin B, dimeric hydrolyzable tannins having a trisgalloyl group

Takashi Yoshida, Tsutomu Hatano, Atallah F. Ahmed, Akira Okonogi, Takuo Okuda

Research output: Contribution to journalArticle

28 Citations (Scopus)


Two new dimeric hydrolyzable tannins, isorugosin E and hirtellin B, have been respectively isolated from Liquidambar formosana (Hamamelidaceae) and Reaumuria hirtella (Tamaricaceae), and their structures 7 and 15, in which two monomers are linked through a trisgalloyl group (valoneoyl or hellinoyl group), have been elucidated based on high resolution NMR techniques. Hirtellin B exhibited a potent host-mediated antitumor activity.

Original languageEnglish
Pages (from-to)3575-3584
Number of pages10
Issue number22
Publication statusPublished - 1991


ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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