Structure of the Chlorella Zepp retrotransposon: Nested Zepp clusters in the genome

Yoshiteru Noutoshi, R. Arai, M. Fujie, T. Yamada

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Zepp elements found in the telomeric region of Chlorella chromosomes show the characteristic features of non-viral (LINE-like) retrotransposons, including a poly(A) tail, 5' truncations, a retroviral reverse transcriptase-like ORF and flanking target duplications. We have isolated and characterized a full-length Zepp element (8943 bp long) from Chlorella chromosome V. Some peculiar features of this element, including nested integration, two ORF structures, a long 3' noncoding region and a possible promoter region are compared with those of the Drosophila telomeric retrotransposons HeT-A and TART. The Chlorella chromosome-Zepp system appears to represent an intermediate stage between canonical telomerase-telomeres and Drosophila retrotransposon-telomeres.

Original languageEnglish
Pages (from-to)256-263
Number of pages8
JournalMGG Molecular & General Genetics
Volume259
Issue number3
DOIs
Publication statusPublished - 1998
Externally publishedYes

Fingerprint

Chlorella
Retroelements
Chromosomes
Telomere
Genome
Open Reading Frames
Drosophila
Telomerase
RNA-Directed DNA Polymerase
Genetic Promoter Regions
Messenger RNA

Keywords

  • Chlorella
  • Full-length copy
  • LINE-like retrotransposon
  • Long 3' noncoding region
  • Nested integration

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology

Cite this

Structure of the Chlorella Zepp retrotransposon : Nested Zepp clusters in the genome. / Noutoshi, Yoshiteru; Arai, R.; Fujie, M.; Yamada, T.

In: MGG Molecular & General Genetics, Vol. 259, No. 3, 1998, p. 256-263.

Research output: Contribution to journalArticle

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AU - Yamada, T.

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