Structural determination of a new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane from Taxus cuspidata

Changhong Huo, Xiaohui Su, Xing Li, Xiping Zhang, Cunfang Li, Yufang Wang, Qingwen Shi, Hiromasa Kiyota

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane were isolated from the methanol extract of the needles of Taxus cuspidata. The structures were established as 2α,7β-diacetoxy-5α,10β,13β-trihydroxy-2(3 → 20)abeotaxa-4(20), 11-dien-9-one (1) and 2α,5α,7β,9α, 13α-pentahydroxy-10β-acetoxytaxa-4(20),11-diene (2) on the basis of 1D and 2D NMR spectral data and high-resolution FAB-MS analyses.

Original languageEnglish
Pages (from-to)527-530
Number of pages4
JournalMagnetic Resonance in Chemistry
Volume45
Issue number6
DOIs
Publication statusPublished - Jun 2007
Externally publishedYes

Fingerprint

FORTRAN
dienes
needles
Needles
Methanol
Substitution reactions
methyl alcohol
Nuclear magnetic resonance
substitutes
nuclear magnetic resonance
rings
high resolution
taxane

Keywords

  • 2α,7β-diacetoxy-5α,10β,13β- trihydroxy-2(3 → 20)abeotaxa-4(20), 11-dien-9-one, 2α,5α, 7β,9α,13α-pentahydroxy-10β-acetoxytaxa-4(20), 11-diene
  • 2D NMR
  • NMR
  • Taxaceae
  • Taxus cuspidata

ASJC Scopus subject areas

  • Chemistry(all)
  • Physical and Theoretical Chemistry
  • Spectroscopy

Cite this

Structural determination of a new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane from Taxus cuspidata. / Huo, Changhong; Su, Xiaohui; Li, Xing; Zhang, Xiping; Li, Cunfang; Wang, Yufang; Shi, Qingwen; Kiyota, Hiromasa.

In: Magnetic Resonance in Chemistry, Vol. 45, No. 6, 06.2007, p. 527-530.

Research output: Contribution to journalArticle

Huo, Changhong ; Su, Xiaohui ; Li, Xing ; Zhang, Xiping ; Li, Cunfang ; Wang, Yufang ; Shi, Qingwen ; Kiyota, Hiromasa. / Structural determination of a new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane from Taxus cuspidata. In: Magnetic Resonance in Chemistry. 2007 ; Vol. 45, No. 6. pp. 527-530.
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abstract = "A new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane were isolated from the methanol extract of the needles of Taxus cuspidata. The structures were established as 2α,7β-diacetoxy-5α,10β,13β-trihydroxy-2(3 → 20)abeotaxa-4(20), 11-dien-9-one (1) and 2α,5α,7β,9α, 13α-pentahydroxy-10β-acetoxytaxa-4(20),11-diene (2) on the basis of 1D and 2D NMR spectral data and high-resolution FAB-MS analyses.",
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AU - Shi, Qingwen

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