Stress proteins and cancer immunology

H. Udono, E. Nakayama

Research output: Contribution to journalArticle

Abstract

Heat shock proteins have been implicated as tumor specific transplantation antigens of which the precise cellular mechanisms have been unknown. For the past several years animal model experiments have revealed some answers to this mystery which will be discussed in this review as follows. Firstly, hsps as carrier proteins for antigenic peptides; secondly, novel priming of CD8+ T cells by hsp peptide complex; and thirdly, involvement of hsps in antigen processing.

Original languageEnglish
Pages (from-to)1286-1292
Number of pages7
JournalBiotherapy
Volume10
Issue number10
Publication statusPublished - Jan 1 1996

Keywords

  • Antigen processing
  • Heat shock proteins
  • Hsp peptide complex
  • Tumor specific transplantation antigen

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Udono, H., & Nakayama, E. (1996). Stress proteins and cancer immunology. Biotherapy, 10(10), 1286-1292.