Stress distribution prevents ischaemia and bone resorption in residual ridge

Yukinori Maruo, Goro Nishigawa, Masao Irie, Morihiko Oka, Tetsuya Hara, Kazuomi Suzuki, Shogo Minagi

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Objective: Intensive mechanical stress and/or inflammation are known to induce alveolar bone resorption. This study investigated whether a distribution of mechanical stress would reduce residual ridge resorption or improve ischaemia. Design: Thirty rats were divided into six experimental groups (n = 5). The control group received no intentional stimulation, but rats in the experimental groups wore denture stimulators made of acrylic resin or a soft lining material. The stimulator transmitted masticatory pressure to the rats' palates for four weeks. The four types of soft lining materials investigated in this study dispersed the applied pressure, with compressive stress ranging from 20.8 to 90.8 kPa. Volumes of blood flow and bone resorption of denture foundations were measured every week for 4 weeks. Statistical evaluation of these results was performed using two-way ANOVA and Holm-Sidak test within 5% error limits. Results: Non-viscoelastic material clearly induced bone resorption and ischaemia of denture foundations, while viscoelastic materials reduced these phenomena to different extents according to their viscoelastic properties. Ischaemia in the alveolar ridge preceded residual ridge resorption, because the amount of residual ridge resorption and blood flow rate showed a simple linear regression. Conclusion: Animal model of this study suggested that a distribution or reduction of mechanical stress could improve blood flow and decrease alveolar ridge resorption.

Original languageEnglish
Pages (from-to)873-878
Number of pages6
JournalArchives of Oral Biology
Volume55
Issue number11
DOIs
Publication statusPublished - Nov 2010

Keywords

  • Bone resorption
  • Ischaemia
  • Mechanical stress
  • Residual ridge

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Dentistry(all)
  • Cell Biology

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