Stratus optical coherence tomography study of filtering blebs after primary trabeculectomy with a fornix-based conjunctival flap

Kazuyuki Hirooka, Mai Takagishi, Tetsuya Baba, Hirokazu Takenaka, Fumio Shiraga

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Purpose: To investigate the relationship between filtering bleb function and Stratus optical coherence tomography (OCT) images. Methods: We studied 72 eyes of 65 consecutive patients who had a fornix-based conjunctival flap in primary trabeculectomy with mitomycin C (MMC). Filtering blebs with various types of glaucoma were examined using Stratus OCT. Success rates were defined as intraocular pressure (IOP) ≤ 15 mmHg and IOP reduction ≥ 25% without medication or additional surgery. Success rates among classified groups were compared using Kaplan-Meier survival curves and the log-rank test. Results: Blebs were classified into three different categories on the basis of the following Stratus OCT patterns: cystoid type (multiple cysts inside the bleb; 17 eyes), diffuse type (low to high reflective areas that were mixed inside the bleb; 31 eyes) and layer type (medium to high reflective layer inside the bleb; 24 eyes). Success rates in the cystoid-, diffuse- and layer-type blebs were 94%, 97% and 75% (P = 0.02), respectively. Conclusion: In trabeculectomy with MMC and a fornix-based conjunctival flap, there is a significant association between the success rates and the postoperative Stratus OCT findings of filtering blebs.

Original languageEnglish
Pages (from-to)60-64
Number of pages5
JournalActa Ophthalmologica
Volume88
Issue number1
DOIs
Publication statusPublished - Feb 2010
Externally publishedYes

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Trabeculectomy
Optical Coherence Tomography
Blister
Mitomycin
Intraocular Pressure
Kaplan-Meier Estimate
Glaucoma
Cysts

Keywords

  • Bleb
  • Glaucoma
  • Optical coherence tomography
  • Trabeculectomy

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Stratus optical coherence tomography study of filtering blebs after primary trabeculectomy with a fornix-based conjunctival flap. / Hirooka, Kazuyuki; Takagishi, Mai; Baba, Tetsuya; Takenaka, Hirokazu; Shiraga, Fumio.

In: Acta Ophthalmologica, Vol. 88, No. 1, 02.2010, p. 60-64.

Research output: Contribution to journalArticle

Hirooka, Kazuyuki ; Takagishi, Mai ; Baba, Tetsuya ; Takenaka, Hirokazu ; Shiraga, Fumio. / Stratus optical coherence tomography study of filtering blebs after primary trabeculectomy with a fornix-based conjunctival flap. In: Acta Ophthalmologica. 2010 ; Vol. 88, No. 1. pp. 60-64.
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