Strain differences in histamine release from peritoneal mast cells in rats

Y. Sugimoto; H. Ohishi; T. Toyota; C. Kamei

doi:10.1016/S0306-3623(98)00063-9

Strain differences in histamine release from peritoneal mast cells in rats

Y. Sugimoto, H. Ohishi, T. Toyota, C. Kamei

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Peritoneal mast cells from Brown-Norway (BN) rats were compared with those from Wistar and Sprague-Dawley (SD) rats.Peritoneal mast cells from BN rats showed the smallest values in number, cell diameter and histamine contents compared with those from Wistar and SD rats.BN rat peritoneal mast cells were more sensitive to compound 48/80 and anti-IgE than were those from Wistar and SD rats, and they showed a higher response to A23187 than did cells from Wistar rats.The histamine release from passively sensitized peritoneal mast cells was weaker in BN rats than was that from Wistar and SD rats. Copyright (C) 1998 Elsevier Science Inc.

Original language	English
Pages (from-to)	613-616
Number of pages	4
Journal	General Pharmacology
Volume	31
Issue number	4
DOIs	https://doi.org/10.1016/S0306-3623(98)00063-9
Publication status	Published - Oct 1 1998

Keywords

Brown-Norway rat
Histamine release
Peritoneal mast cell
Sprague-Dawley rat
Wistar rat

ASJC Scopus subject areas

Pharmacology

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10.1016/S0306-3623(98)00063-9

Cite this

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abstract = "Peritoneal mast cells from Brown-Norway (BN) rats were compared with those from Wistar and Sprague-Dawley (SD) rats.Peritoneal mast cells from BN rats showed the smallest values in number, cell diameter and histamine contents compared with those from Wistar and SD rats.BN rat peritoneal mast cells were more sensitive to compound 48/80 and anti-IgE than were those from Wistar and SD rats, and they showed a higher response to A23187 than did cells from Wistar rats.The histamine release from passively sensitized peritoneal mast cells was weaker in BN rats than was that from Wistar and SD rats. Copyright (C) 1998 Elsevier Science Inc.",

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AU - Sugimoto, Y.

AU - Ohishi, H.

AU - Toyota, T.

AU - Kamei, C.

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Y1 - 1998/10/1

N2 - Peritoneal mast cells from Brown-Norway (BN) rats were compared with those from Wistar and Sprague-Dawley (SD) rats.Peritoneal mast cells from BN rats showed the smallest values in number, cell diameter and histamine contents compared with those from Wistar and SD rats.BN rat peritoneal mast cells were more sensitive to compound 48/80 and anti-IgE than were those from Wistar and SD rats, and they showed a higher response to A23187 than did cells from Wistar rats.The histamine release from passively sensitized peritoneal mast cells was weaker in BN rats than was that from Wistar and SD rats. Copyright (C) 1998 Elsevier Science Inc.

AB - Peritoneal mast cells from Brown-Norway (BN) rats were compared with those from Wistar and Sprague-Dawley (SD) rats.Peritoneal mast cells from BN rats showed the smallest values in number, cell diameter and histamine contents compared with those from Wistar and SD rats.BN rat peritoneal mast cells were more sensitive to compound 48/80 and anti-IgE than were those from Wistar and SD rats, and they showed a higher response to A23187 than did cells from Wistar rats.The histamine release from passively sensitized peritoneal mast cells was weaker in BN rats than was that from Wistar and SD rats. Copyright (C) 1998 Elsevier Science Inc.

KW - Brown-Norway rat

KW - Histamine release

KW - Peritoneal mast cell

KW - Sprague-Dawley rat

KW - Wistar rat

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Strain differences in histamine release from peritoneal mast cells in rats

Abstract

Keywords

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