Strain differences in histamine release from peritoneal mast cells in rats

Yukio Sugimoto, H. Ohishi, T. Toyota, C. Kamei

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Peritoneal mast cells from Brown-Norway (BN) rats were compared with those from Wistar and Sprague-Dawley (SD) rats.Peritoneal mast cells from BN rats showed the smallest values in number, cell diameter and histamine contents compared with those from Wistar and SD rats.BN rat peritoneal mast cells were more sensitive to compound 48/80 and anti-IgE than were those from Wistar and SD rats, and they showed a higher response to A23187 than did cells from Wistar rats.The histamine release from passively sensitized peritoneal mast cells was weaker in BN rats than was that from Wistar and SD rats. Copyright (C) 1998 Elsevier Science Inc.

Original languageEnglish
Pages (from-to)613-616
Number of pages4
JournalGeneral Pharmacology
Volume31
Issue number4
DOIs
Publication statusPublished - Oct 1998

Fingerprint

Histamine Release
Mast Cells
Sprague Dawley Rats
p-Methoxy-N-methylphenethylamine
Calcimycin
Histamine
Wistar Rats
Cell Count

Keywords

  • Brown-Norway rat
  • Histamine release
  • Peritoneal mast cell
  • Sprague-Dawley rat
  • Wistar rat

ASJC Scopus subject areas

  • Pharmacology

Cite this

Strain differences in histamine release from peritoneal mast cells in rats. / Sugimoto, Yukio; Ohishi, H.; Toyota, T.; Kamei, C.

In: General Pharmacology, Vol. 31, No. 4, 10.1998, p. 613-616.

Research output: Contribution to journalArticle

Sugimoto, Yukio ; Ohishi, H. ; Toyota, T. ; Kamei, C. / Strain differences in histamine release from peritoneal mast cells in rats. In: General Pharmacology. 1998 ; Vol. 31, No. 4. pp. 613-616.
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