Symbiodinolide is a polyol marine natural product with a molecular weight of 2860. Herein, a streamlined synthesis of the C79-C97 fragment of symbiodinolide is described. In the synthetic route, a spiroacetalization, a Julia-Kocienski olefination, and a Sharpless asymmetric dihydroxylation were utilized as the key transformations.
- Julia-Kocienski olefination
- Polyol marine natural product
- Sharpless asymmetric dihydroxylation
ASJC Scopus subject areas
- Organic Chemistry