Stereoselective synthesis of (E)-alkenylsilanes from aldehydes with a reagent prepared by chromium(II) reduction of Me3SiCHBr2

Kazuhiko Takai, Yasutaka Kataoka, Takashi Okazoe, Kiitiro Utimoto

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Aldehydes are converted to the corresponding (E)-alkenylsilanes with one carbon homologation by means of a gemdichromium reagent prepared by CrCl2 reduction of Me3SiCHBr2 in THF. Transformation of aldehydes into alkenyl sulfides is also achieved with a combination of PhSCHCl2 and CrCl2.

Original languageEnglish
Pages (from-to)1443-1446
Number of pages4
JournalTetrahedron Letters
Volume28
Issue number13
DOIs
Publication statusPublished - 1987
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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