Stereoselective synthesis of bicyclic tertiary alcohols with quaternary stereocenters via intramolecular crossed benzoin reactions catalyzed by n-heterocyclic carbenes

Tadashi Ema, Yoshitaka Oue, Kumiko Akihara, Yuki Miyazaki, Takashi Sakai

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Bicyclic tertiary alcohols 1 bearing quaternary stereocenters at the two adjacent bridgehead positions were synthesized with high stereoselectivity via the intramolecular crossed benzoin reactions catalyzed by NHC organocatalysts.

Original languageEnglish
Pages (from-to)4866-4869
Number of pages4
JournalOrganic Letters
Volume11
Issue number21
DOIs
Publication statusPublished - Nov 5 2009

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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