Stereoselective synthesis of 3-alkylideneoxindoles by rhodium-catalyzed cyclization reaction of 2-alkynylaryl isocyanates with aryland alkenylboronic acids

Tomoya Miura, Yusuke Takahashi, Masahiro Murakami

Research output: Contribution to journalArticlepeer-review

60 Citations (Scopus)

Abstract

The rhodium-catalyzed cyclization reaction of 2-alkynylaryl isocyanates with aryl- and alkenylboronic acids furnishes 3-alkylideneoxindoles in a stereoselective manner. The reaction allows arrangement of various substituents on the exocyclic double bond and aromatic ring with wide functional tolerance.

Original languageEnglish
Pages (from-to)5075-5077
Number of pages3
JournalOrganic Letters
Volume9
Issue number24
DOIs
Publication statusPublished - Nov 22 2007
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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