Abstract
(Chemical Equation Presented) A palladium(0)/monophosphine catalyst promotes a cyclization reaction of 2-(alkynyl)aryl isocyanates with organoboron reagents to produce stereodefined 3-alkylideneoxindoles. The alkynyl and isocyanato groups undergo oxidative cyclization with Pd(O) to form an oxapalladacycle intermediate. Subsequent transmetalation and reductive elimination afford the product.
Original language | English |
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Pages (from-to) | 4887-4889 |
Number of pages | 3 |
Journal | Organic Letters |
Volume | 10 |
Issue number | 21 |
DOIs | |
Publication status | Published - 2008 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry