Stereoselective synthesis and absolute configuration of the C1′-C25′ fragment of symbiodinolide

Hiroyoshi Takamura, Takeshi Murata, Takahiro Asai, Isao Kadota, Daisuke Uemura

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

(Chemical Equation Presented) Stereoselective synthesis of the C1′-C25′ fragment of symbiodinolide, which was obtained as a degraded product from symbiodinolide by alkaline hydrolysis, has been accomplished. The synthetic route features Kotsuki coupling and Julia-Kocienski olefination in the introduction of the side chains. This enantioand stereoselective synthesis has established the absolute configuration of the C1′-C25′ fragment.

Original languageEnglish
Pages (from-to)6658-6666
Number of pages9
JournalJournal of Organic Chemistry
Volume74
Issue number17
DOIs
Publication statusPublished - Sep 4 2009

ASJC Scopus subject areas

  • Organic Chemistry

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