Abstract
Efficient trapping of chromium enolates in the presence of Et3SiCl gives silyl enol ethers. This trapping changes the course of the reaction between α,β-unsaturated ketones and aldehydes from a sequential aldol-cyclopropanol formation to a cross pinacol-type coupling reaction (Eq. (1); for example, R1=n-C8H17,R2=Ph(CH2) 2]. The antilsyn ratios of the 1,2-diols depend on the reaction temperature.
Original language | English |
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Pages (from-to) | 1116-1119 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 40 |
Issue number | 6 |
DOIs | |
Publication status | Published - Mar 14 2001 |
Keywords
- Aldehydes
- Chromium
- Diols
- Ketones
- Pinacol coupling
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)