Staphylococcus aureus aggregation in the plasma fraction of silkworm hemolymph

Hiroki Ryuno, Fuki Nigo, Isao Naguro, Kazuhisa Sekimizu, Chikara Kaito

Research output: Contribution to journalArticle

Abstract

Staphylococcus aureus formed bacterial aggregates in the plasma fraction of the hemolymph of silkworm, the larva of Bombyx mori, in a growth-dependent manner. The addition of arabinose or galactose inhibited the formation of S. aureus aggregates in the silkworm plasma. Formation of the bacterial aggregates depended on S. aureus genes required for the synthesis of bacterial surface polysaccharides-ypfP and ltaA, which are involved in lipoteichoic acid synthesis, and the tagO gene, which is involved in wall teichoic acid synthesis. These findings suggest that S. aureus forms bacterial aggregates in the silkworm plasma via bacterial surface teichoic acids.

Original languageEnglish
Article numbere0217517
JournalPloS one
Volume14
Issue number5
DOIs
Publication statusPublished - May 2019

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Bombyx
Hemolymph
silkworms
hemolymph
Staphylococcus aureus
Agglomeration
Teichoic Acids
Plasmas
synthesis
Genes
Bacterial Polysaccharides
Arabinose
arabinose
Bombyx mori
Galactose
galactose
Polysaccharides
Larva
insect larvae
polysaccharides

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Staphylococcus aureus aggregation in the plasma fraction of silkworm hemolymph. / Ryuno, Hiroki; Nigo, Fuki; Naguro, Isao; Sekimizu, Kazuhisa; Kaito, Chikara.

In: PloS one, Vol. 14, No. 5, e0217517, 05.2019.

Research output: Contribution to journalArticle

Ryuno, Hiroki ; Nigo, Fuki ; Naguro, Isao ; Sekimizu, Kazuhisa ; Kaito, Chikara. / Staphylococcus aureus aggregation in the plasma fraction of silkworm hemolymph. In: PloS one. 2019 ; Vol. 14, No. 5.
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