Abstract
Multichannel intraluminal impedance-pH measurements (MII-pH) are useful for evaluating acid and non-acid gastroesophageal reflux (GER). However, the use of MIH-pH is not yet established in Japan. The Japanese Pediatric Impedance Working Group (Japanese-PIG) convened to devise a standard protocol for MII-pH in Japanese children. The expert members of the Japanese-PIG collected data on pediatric MII-pH from the relevant literature in English, including the standard protocol of MII-pH presented by the European PIG, and the insights of international experts. The resultant consensus was included in the contents of the standard protocol of MII-pH. The standard protocol included standardization of the indication, methodology, and interpretation of MII-pH in Japanese children. The criteria for abnormal GER by MII-pH were defined using the Reflux Index and number of total reflux episodes independently in children aged < 1 year and those aged ≥ 1 year. Moreover, a significant relationship between GER and symptoms was identified using the symptom index and symptom association probability approach. We conclude that the current version of the protocol for MII-pH is tentative because it is not based on data from Japanese children. Further studies are needed to render this protocol clinically beneficial and expand its use in Japan.
| Original language | English |
|---|---|
| Journal | Surgery today |
| DOIs | |
| Publication status | Published - Jan 1 2019 |
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Keywords
- Children
- Gastroesophageal reflux
- Multichannel intraluminal impedance-pH measurements
- Standard protocol
ASJC Scopus subject areas
- Surgery
Cite this
Standard protocol devised by the Japanese Pediatric Impedance Working Group for combined multichannel intraluminal impedance-pH measurements in children. / Japanese Pediatric Impedance Working Group (Japanese-PIG).
In: Surgery today, 01.01.2019.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Standard protocol devised by the Japanese Pediatric Impedance Working Group for combined multichannel intraluminal impedance-pH measurements in children
AU - Japanese Pediatric Impedance Working Group (Japanese-PIG)
AU - Fukahori, Suguru
AU - Kawahara, Hisayoshi
AU - Oyama, Takanori
AU - Saito, Takeshi
AU - Shimono, Ryuichi
AU - Tanaka, Aya
AU - Noda, Takuo
AU - Hatori, Reiko
AU - Fujino, Junko
AU - Yagi, Minoru
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Multichannel intraluminal impedance-pH measurements (MII-pH) are useful for evaluating acid and non-acid gastroesophageal reflux (GER). However, the use of MIH-pH is not yet established in Japan. The Japanese Pediatric Impedance Working Group (Japanese-PIG) convened to devise a standard protocol for MII-pH in Japanese children. The expert members of the Japanese-PIG collected data on pediatric MII-pH from the relevant literature in English, including the standard protocol of MII-pH presented by the European PIG, and the insights of international experts. The resultant consensus was included in the contents of the standard protocol of MII-pH. The standard protocol included standardization of the indication, methodology, and interpretation of MII-pH in Japanese children. The criteria for abnormal GER by MII-pH were defined using the Reflux Index and number of total reflux episodes independently in children aged < 1 year and those aged ≥ 1 year. Moreover, a significant relationship between GER and symptoms was identified using the symptom index and symptom association probability approach. We conclude that the current version of the protocol for MII-pH is tentative because it is not based on data from Japanese children. Further studies are needed to render this protocol clinically beneficial and expand its use in Japan.
AB - Multichannel intraluminal impedance-pH measurements (MII-pH) are useful for evaluating acid and non-acid gastroesophageal reflux (GER). However, the use of MIH-pH is not yet established in Japan. The Japanese Pediatric Impedance Working Group (Japanese-PIG) convened to devise a standard protocol for MII-pH in Japanese children. The expert members of the Japanese-PIG collected data on pediatric MII-pH from the relevant literature in English, including the standard protocol of MII-pH presented by the European PIG, and the insights of international experts. The resultant consensus was included in the contents of the standard protocol of MII-pH. The standard protocol included standardization of the indication, methodology, and interpretation of MII-pH in Japanese children. The criteria for abnormal GER by MII-pH were defined using the Reflux Index and number of total reflux episodes independently in children aged < 1 year and those aged ≥ 1 year. Moreover, a significant relationship between GER and symptoms was identified using the symptom index and symptom association probability approach. We conclude that the current version of the protocol for MII-pH is tentative because it is not based on data from Japanese children. Further studies are needed to render this protocol clinically beneficial and expand its use in Japan.
KW - Children
KW - Gastroesophageal reflux
KW - Multichannel intraluminal impedance-pH measurements
KW - Standard protocol
UR - http://www.scopus.com/inward/record.url?scp=85067677472&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85067677472&partnerID=8YFLogxK
U2 - 10.1007/s00595-019-01833-6
DO - 10.1007/s00595-019-01833-6
M3 - Review article
JO - Japanese Journal of Surgery
JF - Japanese Journal of Surgery
SN - 0941-1291
ER -