Stage IB1 cervical cancer patients with an MRI-measured tumor size ≤ 2 cm might be candidates for less-radical surgery

J. Kodama, Chikako Ogawa, T. Kusumoto, Keiichiro Nakamura, N. Seki, A. Hongo, Y. Hiramatsu

Research output: Contribution to journalArticle

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Abstract

Objectives: To examine the correlation between histopathology and magnetic resonance imaging (MRI) measured tumor size and define whether patients with Stage IB1 cervical cancer with an MRI-measured tumor size ≤ 2 cm can be candidates for less-radical surgery. Materials and Methods: The authors retrospectively reviewed 200 patients with Stage IB1 cervical cancer who underwent radical hysterectomy (class III) and pelvic lymphadenectomy. The largest diameter of the tumor was determined by MRI in 52 consecutive cases. Results: Regarding risk factors for parametrial involvement, only tumor size and age are known before definitive surgery without conization. Multivariate analysis of these risk factors revealed that both tumor size and old age were independently associated with parametrial involvement. Eighty-eight patients had a tumor size ≤ 2 cm and an age ≤ 50 years, two of which (2.3%) had parametrial involvement. In 52 consecutive patients, a significant correlation between histopathology- and MRI-measured tumor size was found (r = 0.787). Twenty-three patients had an MRI-measured tumor size ≤ 2 cm, none of which had parametrial involvement. Conclusions: Patients with Stage IB1 cervical cancer lesions with a tumor size ≤ 2 cm measured by MRI and age ≤ 50 years can be treated with less-radical surgery.

Original languageEnglish
Pages (from-to)39-41
Number of pages3
JournalEuropean Journal of Gynaecological Oncology
Volume34
Issue number1
Publication statusPublished - 2013

Fingerprint

Uterine Cervical Neoplasms
Magnetic Resonance Imaging
Neoplasms
Conization
Lymph Node Excision
Hysterectomy
Multivariate Analysis

Keywords

  • Cervical cancer
  • Less-radical surgery
  • MRI

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Oncology

Cite this

Stage IB1 cervical cancer patients with an MRI-measured tumor size ≤ 2 cm might be candidates for less-radical surgery. / Kodama, J.; Ogawa, Chikako; Kusumoto, T.; Nakamura, Keiichiro; Seki, N.; Hongo, A.; Hiramatsu, Y.

In: European Journal of Gynaecological Oncology, Vol. 34, No. 1, 2013, p. 39-41.

Research output: Contribution to journalArticle

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AU - Ogawa, Chikako

AU - Kusumoto, T.

AU - Nakamura, Keiichiro

AU - Seki, N.

AU - Hongo, A.

AU - Hiramatsu, Y.

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N2 - Objectives: To examine the correlation between histopathology and magnetic resonance imaging (MRI) measured tumor size and define whether patients with Stage IB1 cervical cancer with an MRI-measured tumor size ≤ 2 cm can be candidates for less-radical surgery. Materials and Methods: The authors retrospectively reviewed 200 patients with Stage IB1 cervical cancer who underwent radical hysterectomy (class III) and pelvic lymphadenectomy. The largest diameter of the tumor was determined by MRI in 52 consecutive cases. Results: Regarding risk factors for parametrial involvement, only tumor size and age are known before definitive surgery without conization. Multivariate analysis of these risk factors revealed that both tumor size and old age were independently associated with parametrial involvement. Eighty-eight patients had a tumor size ≤ 2 cm and an age ≤ 50 years, two of which (2.3%) had parametrial involvement. In 52 consecutive patients, a significant correlation between histopathology- and MRI-measured tumor size was found (r = 0.787). Twenty-three patients had an MRI-measured tumor size ≤ 2 cm, none of which had parametrial involvement. Conclusions: Patients with Stage IB1 cervical cancer lesions with a tumor size ≤ 2 cm measured by MRI and age ≤ 50 years can be treated with less-radical surgery.

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