ST-1, a Novel Radical Scavenger From Fungus F-124

Akio Kobayashi, Yutaka Koguchi, Shigeo Takahashi, Hiroshi Kanzaki, Kazuyoshi Kawazu

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


Peroxidase (POD) plays an important role in the biosynthesis of disease-lignin, which protects plants from fungal invasion. A novel POD inhibitor, ST-1 (1), was isolated from a fungus, and its chemical structure was elucidated to be 1,3-dihydro-4,5,6-trihydroxy-1,3-dimethoxy-7-methylisobenzofuran by a combination of chemical modification and spectroscopic techniques. ST-1 effectively scavenged oxygen radicals and also suppressed the phytoalexin accumulation in kidney bean.
Original languageEnglish
Pages (from-to)1034-1036
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Issue number6
Publication statusPublished - Jun 23 1993
Externally publishedYes


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