TY - JOUR
T1 - Spontaneous rupture of a hepatic angiomyolipoma
T2 - Report of a case
AU - Aoki, Hideki
AU - Arata, Takashi
AU - Morihiro, Toshiaki
AU - Kanaya, Nobuhiko
AU - Takeda, Sho
AU - Sui, Kenta
AU - Shigeyasu, Kunitoshi
AU - Katsuda, Koh
AU - Tanakaya, Kohji
AU - Takeuchi, Hitoshi
N1 - Publisher Copyright:
© 2014, Springer Japan.
PY - 2014/10/8
Y1 - 2014/10/8
N2 - A 70-year-old female experienced sudden onset of back pain on the right side and was admitted to our hospital in December 2010. Abdominal computed tomography revealed an S7 hepatic mass measuring 7 cm in diameter accompanied by a subcapsular hematoma. Emergency angiography confirmed the diagnosis of a ruptured hepatic mass, and hemostasis was carried out by embolization of A8 and A7 of the liver. A right hepatic lobectomy was carried out 39 days following transarterial embolization. Although almost all aspects of the tumor were necrotic, residual tumor cells stained positive for HMB-45, and negative for α-SMA, S-100, CD 34, c-kit, CAM 5.2, and hepatocytes. The MIB-1 index was 2 %. Pathological diagnosis was hepatic angiomyolipoma (HAML). The patient has shown no signs of recurrence at 42 months following surgery. Here, we report on this case of spontaneous HAML rupture and discuss therapeutic strategies for HAML and ruptured hepatic tumors.
AB - A 70-year-old female experienced sudden onset of back pain on the right side and was admitted to our hospital in December 2010. Abdominal computed tomography revealed an S7 hepatic mass measuring 7 cm in diameter accompanied by a subcapsular hematoma. Emergency angiography confirmed the diagnosis of a ruptured hepatic mass, and hemostasis was carried out by embolization of A8 and A7 of the liver. A right hepatic lobectomy was carried out 39 days following transarterial embolization. Although almost all aspects of the tumor were necrotic, residual tumor cells stained positive for HMB-45, and negative for α-SMA, S-100, CD 34, c-kit, CAM 5.2, and hepatocytes. The MIB-1 index was 2 %. Pathological diagnosis was hepatic angiomyolipoma (HAML). The patient has shown no signs of recurrence at 42 months following surgery. Here, we report on this case of spontaneous HAML rupture and discuss therapeutic strategies for HAML and ruptured hepatic tumors.
KW - HMB-45
KW - Hepatic angiomyolipoma
KW - Rupture
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U2 - 10.1007/s12328-014-0517-z
DO - 10.1007/s12328-014-0517-z
M3 - Article
C2 - 26184024
AN - SCOPUS:84919845135
SN - 1865-7257
VL - 7
SP - 429
EP - 433
JO - Clinical Journal of Gastroenterology
JF - Clinical Journal of Gastroenterology
IS - 5
ER -