Spectrophotometric determination of chlorpromazine in preparation with o-sulfophenylfluorone and Gallium(III)

Naoko Suzaki, Shinya Kadi, Kanako Miyachi, Kenzo Moriyama, Shinichiro Kamino, Takako Yamaguchi, Yoshikazu Fujita

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


A novel spectrophotometric method was established for the determination of chlorpromazine (CP) and other drugs with an o-sulfophenylfluorone-gallium(III) complex. In the determination of CP, Beer's law is obeyed in the range of 0.08~2.0 μg/mL. The molar absorptivity and the relative standard deviation were 1.2×105 dm3 mol-1 cm-1 and 2.5% (n = 5), respectivery. Moreover, the method was successfully applied to assays of CP and other drugs in pharmaceutical preparations. The proposed method should be useful for simple and sensitive determinations of CP and other drugs.

Original languageEnglish
Pages (from-to)727-732
Number of pages6
Issue number8
Publication statusPublished - 2010
Externally publishedYes


  • Chlorpromazine
  • O-sulfophenylfluorone-gallium(III)-complex
  • Spectrophotometry

ASJC Scopus subject areas

  • Analytical Chemistry


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