Spa therapy improves ventilatory function in the small airways of patients with steroid-dependent intractable asthma (SDIA).

Y. Tanizaki, H. Kitani, M. Okazaki, T. Mifune, Fumihiro Mitsunobu, K. Ochi, H. Harada, I. Kimura

Research output: Contribution to journalArticle

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Abstract

The improvement of ventilatory function by spa therapy was examined in 37 patients with steroid-dependent intractable asthma (SDIA) in relation to clinical asthma types. All subjects had been on long-term corticosteroid therapy before spa therapy. Spa therapy was found to improve the values of ventilatory parameters. The percent improvement in all subjects was +4.1% in %FVC, +8.9% in FEV1.0%, +9.8% in %PEFR, +22.0% in %MMF, +19.7% in %V50 and +28.2% in %V25, respectively. Relating to clinical asthma types, moderate improvement in %MMF and %V25 from 16.7% to 16.9% was observed in type Ia cases, and marked increase in %MMF, %V50 and %V25 was observed from 42.2% to 43.2% in type Ib cases. However, no significant increase was found in these parameters of types Ia or Ib after spa therapy. In patients with type II, a significant increase was shown in %V50 (p less than 0.05) and %V25 (p less than 0.01) after spa therapy. The results show that spa therapy improves the condition of small airways disorder in patients with SDIA.

Original languageEnglish
Pages (from-to)175-178
Number of pages4
JournalActa Medica Okayama
Volume46
Issue number3
Publication statusPublished - Jun 1992

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Asthma
Steroids
Adrenal Cortex Hormones
Therapeutics
Peak Expiratory Flow Rate

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Spa therapy improves ventilatory function in the small airways of patients with steroid-dependent intractable asthma (SDIA). / Tanizaki, Y.; Kitani, H.; Okazaki, M.; Mifune, T.; Mitsunobu, Fumihiro; Ochi, K.; Harada, H.; Kimura, I.

In: Acta Medica Okayama, Vol. 46, No. 3, 06.1992, p. 175-178.

Research output: Contribution to journalArticle

Tanizaki, Y, Kitani, H, Okazaki, M, Mifune, T, Mitsunobu, F, Ochi, K, Harada, H & Kimura, I 1992, 'Spa therapy improves ventilatory function in the small airways of patients with steroid-dependent intractable asthma (SDIA).', Acta Medica Okayama, vol. 46, no. 3, pp. 175-178.
Tanizaki, Y. ; Kitani, H. ; Okazaki, M. ; Mifune, T. ; Mitsunobu, Fumihiro ; Ochi, K. ; Harada, H. ; Kimura, I. / Spa therapy improves ventilatory function in the small airways of patients with steroid-dependent intractable asthma (SDIA). In: Acta Medica Okayama. 1992 ; Vol. 46, No. 3. pp. 175-178.
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