Spa therapy improves ventilatory function in the small airways of patients with steroid-dependent intractable asthma (SDIA).

Y. Tanizaki, H. Kitani, M. Okazaki, T. Mifune, F. Mitsunobu, K. Ochi, H. Harada, I. Kimura

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Abstract

The improvement of ventilatory function by spa therapy was examined in 37 patients with steroid-dependent intractable asthma (SDIA) in relation to clinical asthma types. All subjects had been on long-term corticosteroid therapy before spa therapy. Spa therapy was found to improve the values of ventilatory parameters. The percent improvement in all subjects was +4.1% in %FVC, +8.9% in FEV1.0%, +9.8% in %PEFR, +22.0% in %MMF, +19.7% in %V50 and +28.2% in %V25, respectively. Relating to clinical asthma types, moderate improvement in %MMF and %V25 from 16.7% to 16.9% was observed in type Ia cases, and marked increase in %MMF, %V50 and %V25 was observed from 42.2% to 43.2% in type Ib cases. However, no significant increase was found in these parameters of types Ia or Ib after spa therapy. In patients with type II, a significant increase was shown in %V50 (p less than 0.05) and %V25 (p less than 0.01) after spa therapy. The results show that spa therapy improves the condition of small airways disorder in patients with SDIA.

Original languageEnglish
Pages (from-to)175-178
Number of pages4
JournalActa medica Okayama
Volume46
Issue number3
Publication statusPublished - Jun 1992

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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    Tanizaki, Y., Kitani, H., Okazaki, M., Mifune, T., Mitsunobu, F., Ochi, K., Harada, H., & Kimura, I. (1992). Spa therapy improves ventilatory function in the small airways of patients with steroid-dependent intractable asthma (SDIA). Acta medica Okayama, 46(3), 175-178.