Solvent-Free Benzoin and Stetter Reactions with a Small Amount of NHC Catalyst in the Liquid or Semisolid State

Tadashi Ema, Yoshiko Nanjo, Sho Shiratori, Yuta Terao, Ryo Kimura

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The intermolecular or intramolecular asymmetric benzoin reaction was catalyzed by a small amount of N-heterocyclic carbene (NHC) (0.2-1 mol %) under solvent-free conditions. The solvent-free intramolecular asymmetric Stetter reaction also proceeded efficiently with NHC (0.2-1 mol %). In some cases, even solid-to-solid or solid-to-liquid conversions took place with low catalyst loading (0.2-1 mol %).

Original languageEnglish
Pages (from-to)5764-5767
Number of pages4
JournalOrganic Letters
Volume18
Issue number21
DOIs
Publication statusPublished - Nov 4 2016
Externally publishedYes

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Benzoin
semisolids
carbenes
catalysts
Catalysts
Liquids
liquids
carbene

Keywords

  • Journal Article

Cite this

Solvent-Free Benzoin and Stetter Reactions with a Small Amount of NHC Catalyst in the Liquid or Semisolid State. / Ema, Tadashi; Nanjo, Yoshiko; Shiratori, Sho; Terao, Yuta; Kimura, Ryo.

In: Organic Letters, Vol. 18, No. 21, 04.11.2016, p. 5764-5767.

Research output: Contribution to journalArticle

Ema, Tadashi ; Nanjo, Yoshiko ; Shiratori, Sho ; Terao, Yuta ; Kimura, Ryo. / Solvent-Free Benzoin and Stetter Reactions with a Small Amount of NHC Catalyst in the Liquid or Semisolid State. In: Organic Letters. 2016 ; Vol. 18, No. 21. pp. 5764-5767.
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