Solvent-Free Benzoin and Stetter Reactions with a Small Amount of NHC Catalyst in the Liquid or Semisolid State

Tadashi Ema, Yoshiko Nanjo, Sho Shiratori, Yuta Terao, Ryo Kimura

Research output: Contribution to journal › Article

17 Citations (Scopus)

Abstract

The intermolecular or intramolecular asymmetric benzoin reaction was catalyzed by a small amount of N-heterocyclic carbene (NHC) (0.2-1 mol %) under solvent-free conditions. The solvent-free intramolecular asymmetric Stetter reaction also proceeded efficiently with NHC (0.2-1 mol %). In some cases, even solid-to-solid or solid-to-liquid conversions took place with low catalyst loading (0.2-1 mol %).

Original languageEnglish
Pages (from-to)5764-5767
Number of pages4
JournalOrganic Letters
Volume18
Issue number21
DOIs
Publication statusPublished - Nov 4 2016
Externally publishedYes

Fingerprint

Benzoin
semisolids
carbenes
catalysts
Catalysts
Liquids
liquids
carbene

Keywords

  • Journal Article

Cite this

Solvent-Free Benzoin and Stetter Reactions with a Small Amount of NHC Catalyst in the Liquid or Semisolid State. / Ema, Tadashi; Nanjo, Yoshiko; Shiratori, Sho; Terao, Yuta; Kimura, Ryo.

In: Organic Letters, Vol. 18, No. 21, 04.11.2016, p. 5764-5767.

Research output: Contribution to journal › Article

Ema, T, Nanjo, Y, Shiratori, S, Terao, Y & Kimura, R 2016, 'Solvent-Free Benzoin and Stetter Reactions with a Small Amount of NHC Catalyst in the Liquid or Semisolid State', Organic Letters, vol. 18, no. 21, pp. 5764-5767. https://doi.org/10.1021/acs.orglett.6b03115
Ema T, Nanjo Y, Shiratori S, Terao Y, Kimura R. Solvent-Free Benzoin and Stetter Reactions with a Small Amount of NHC Catalyst in the Liquid or Semisolid State. Organic Letters. 2016 Nov 4;18(21):5764-5767. https://doi.org/10.1021/acs.orglett.6b03115
Ema, Tadashi ; Nanjo, Yoshiko ; Shiratori, Sho ; Terao, Yuta ; Kimura, Ryo. / Solvent-Free Benzoin and Stetter Reactions with a Small Amount of NHC Catalyst in the Liquid or Semisolid State. In: Organic Letters. 2016 ; Vol. 18, No. 21. pp. 5764-5767.
@article{82b68e3bad62486c9a3442f2c8d13244,
title = "Solvent-Free Benzoin and Stetter Reactions with a Small Amount of NHC Catalyst in the Liquid or Semisolid State",
abstract = "The intermolecular or intramolecular asymmetric benzoin reaction was catalyzed by a small amount of N-heterocyclic carbene (NHC) (0.2-1 mol {\%}) under solvent-free conditions. The solvent-free intramolecular asymmetric Stetter reaction also proceeded efficiently with NHC (0.2-1 mol {\%}). In some cases, even solid-to-solid or solid-to-liquid conversions took place with low catalyst loading (0.2-1 mol {\%}).",
keywords = "Journal Article",
author = "Tadashi Ema and Yoshiko Nanjo and Sho Shiratori and Yuta Terao and Ryo Kimura",
year = "2016",
month = "11",
day = "4",
doi = "10.1021/acs.orglett.6b03115",
language = "English",
volume = "18",
pages = "5764--5767",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "21",

}

TY - JOUR

T1 - Solvent-Free Benzoin and Stetter Reactions with a Small Amount of NHC Catalyst in the Liquid or Semisolid State

AU - Ema, Tadashi

AU - Nanjo, Yoshiko

AU - Shiratori, Sho

AU - Terao, Yuta

AU - Kimura, Ryo

PY - 2016/11/4

Y1 - 2016/11/4

N2 - The intermolecular or intramolecular asymmetric benzoin reaction was catalyzed by a small amount of N-heterocyclic carbene (NHC) (0.2-1 mol %) under solvent-free conditions. The solvent-free intramolecular asymmetric Stetter reaction also proceeded efficiently with NHC (0.2-1 mol %). In some cases, even solid-to-solid or solid-to-liquid conversions took place with low catalyst loading (0.2-1 mol %).

AB - The intermolecular or intramolecular asymmetric benzoin reaction was catalyzed by a small amount of N-heterocyclic carbene (NHC) (0.2-1 mol %) under solvent-free conditions. The solvent-free intramolecular asymmetric Stetter reaction also proceeded efficiently with NHC (0.2-1 mol %). In some cases, even solid-to-solid or solid-to-liquid conversions took place with low catalyst loading (0.2-1 mol %).

KW - Journal Article

U2 - 10.1021/acs.orglett.6b03115

DO - 10.1021/acs.orglett.6b03115

M3 - Article

VL - 18

SP - 5764

EP - 5767

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 21

ER -

Access to Document