Sol-gel synthesis and microstructure analysis of amino-modified hybrid silica nanoparticles from aminopropyltriethoxysilane and tetraethoxysilane

Song Chen, Satoshi Hayakawa, Yuki Shirosaki, Eiji Fujii, Koji Kawabata, Kanji Tsuru, Akiyoshi Osaka

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49 Citations (Scopus)


Agglomerated amino-modified silica nanoparticles were prepared from a novel Stöber-like precursor system consisting of aminopropyltriethoxysilane (APTES), tetraethoxysilane (TEOS), ethanol, and water where the molar ratio APTES/TEOS was 0, 0.1, 1.0, and 2.0, and the molar ratio H2O/- SiOC2H5 was about 20 to 60, or great excess amounts of H2O were employed. APTES catalyzed the hydrolysis and condensation of both silanes. 29Si magic angle spinning nuclear magnetic resonance spectra confirmed that the particles consisted of Qn species (Si(OSi)n(OH)4-n; n=2, 3, 4) and Tn species (NH2(CH2)3-Si(OSi)n(OH) 3-n; n=2, 3). The APTES content in the precursor solutions controlled the agglomerating spherical particle size and morphology: 0.1 in the ratio APTES/TEOS led to almost independent spheres of 300-400 nm, while the larger ratios 1 and 2 led to ∼250 and ∼150 nm spheres, respectively, that were largely agglomerated and some were fused to look like peanut-shells. When soaked in Kokubo's simulated body fluid, those amino-modified particles deposited apatite. The mechanisms of particle formation and apatite deposition were discussed in terms of an intraparticle hydrated layer.

Original languageEnglish
Pages (from-to)2074-2082
Number of pages9
JournalJournal of the American Ceramic Society
Issue number9
Publication statusPublished - Sep 1 2009


ASJC Scopus subject areas

  • Ceramics and Composites
  • Materials Chemistry

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