Sleep problems in subacute myelo-optico neuropathy (SMON)

Research output: Contribution to journalArticle

Abstract

Subacute myelo-optico neuropathy (SMON) patients typically suffer from sequelae that cause sleep disturbances. We sought to examine the prevalence of sleep problems among SMON patients. We conducted a questionnaire-based survey concerning sleep problems among 106 SMON patients, and 110 age- and gender-matched control participants. The prevalence of subjective insomnia (6 ≤ Athens Insomnia Scale score) was 89.6% among SMON patients, which was significantly higher than among control participants 54.4%. Sleep quality measured with the Pittsburgh Sleep Quality Index (PSQI) revealed that the prevalence of poor sleepers (6 ≤ PSQI score) was higher among SMON patients than control participants (75.6% vs 39.6%, respectively). Subscale analyses of rapid eye movement sleep behavior disorder screening questionnaire revealed that scores on two items (“dreams match nocturnal behavior” and “limb movements”) were significantly higher among SMON patients than control participants. In addition, daytime sleepiness scores were significantly higher among SMON patients than control participants (4 ≤ Epworth Sleepiness Scale scores: 54.0% vs 29.0%, respectively). The current study revealed that most SMON patients suffer from insomnia with dissatisfactory sleep quality, likely due to their long-term physical sequelae. Moreover, SMON patients showed higher rates of daytime sleepiness and sleep medication intake, which could be related to reduced activity during the day, as well as insomnia.

Original languageEnglish
JournalJournal of Clinical Neuroscience
DOIs
Publication statusPublished - Jan 1 2019

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Sleep
Sleep Initiation and Maintenance Disorders
REM Sleep Behavior Disorder
Extremities

Keywords

  • Excessive daytime sleepiness
  • Insomnia
  • Rapid eye movement sleep behavior disorder
  • Sleep quality
  • Subacute myelo-optico neuropathy

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

Cite this

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title = "Sleep problems in subacute myelo-optico neuropathy (SMON)",
abstract = "Subacute myelo-optico neuropathy (SMON) patients typically suffer from sequelae that cause sleep disturbances. We sought to examine the prevalence of sleep problems among SMON patients. We conducted a questionnaire-based survey concerning sleep problems among 106 SMON patients, and 110 age- and gender-matched control participants. The prevalence of subjective insomnia (6 ≤ Athens Insomnia Scale score) was 89.6{\%} among SMON patients, which was significantly higher than among control participants 54.4{\%}. Sleep quality measured with the Pittsburgh Sleep Quality Index (PSQI) revealed that the prevalence of poor sleepers (6 ≤ PSQI score) was higher among SMON patients than control participants (75.6{\%} vs 39.6{\%}, respectively). Subscale analyses of rapid eye movement sleep behavior disorder screening questionnaire revealed that scores on two items (“dreams match nocturnal behavior” and “limb movements”) were significantly higher among SMON patients than control participants. In addition, daytime sleepiness scores were significantly higher among SMON patients than control participants (4 ≤ Epworth Sleepiness Scale scores: 54.0{\%} vs 29.0{\%}, respectively). The current study revealed that most SMON patients suffer from insomnia with dissatisfactory sleep quality, likely due to their long-term physical sequelae. Moreover, SMON patients showed higher rates of daytime sleepiness and sleep medication intake, which could be related to reduced activity during the day, as well as insomnia.",
keywords = "Excessive daytime sleepiness, Insomnia, Rapid eye movement sleep behavior disorder, Sleep quality, Subacute myelo-optico neuropathy",
author = "Nozomi Hishikawa and Mami Takemoto and Kota Sato and Toru Yamashita and Yasuyuki Ohta and Kenichi Sakai and Koji Abe",
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AU - Sakai, Kenichi

AU - Abe, Koji

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