TY - JOUR
T1 - Sleep duration, sleep quality and cardiovascular disease mortality among the elderly
T2 - A population-based cohort study
AU - Suzuki, Etsuji
AU - Yorifuji, Takashi
AU - Ueshima, Kazumune
AU - Takao, Soshi
AU - Sugiyama, Masumi
AU - Ohta, Toshiki
AU - Ishikawa-Takata, Kazuko
AU - Doi, Hiroyuki
N1 - Funding Information:
This work was supported by grants-in-aid from the Ministry of Health, Labour and Welfare of Japan (Health and Labour Sciences Research Grants, Comprehensive Research on Aging and Health).
Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2009/8
Y1 - 2009/8
N2 - Objective: To investigate the associations between sleep duration and mortality in the elderly by controlling for sleep quality. Method: Data were collected from participants in a cohort study in Shizuoka, Japan. A total of 14,001 elderly residents (aged 65-85 years), randomly chosen from all 74 municipalities in the prefecture, completed questionnaires that evaluated sleep duration, sleep complaints, and the use of hypnotics. Participants were followed from 1999 to 2006. We analyzed 11,395 subjects to estimate the hazard ratios (HR) for mortality from all causes and cardiovascular disease (CVD). Results: With 60,252 person-years, 1004 deaths were identified. While short sleep duration and mortality were not associated, longer sleep duration was associated with higher risk of mortality in both sexes. Compared with those who slept 7 h, the multivariate HR and 95% confidence interval of CVD mortality for those who slept ≥ 10 h was 1.95 (1.18-3.21) and, for those who slept ≤ 5 h, it was 1.10 (0.62-1.93). Although no clear association was found between sleep quality and mortality, long sleep duration was associated with higher risk of CVD mortality among those with poor sleep quality. Conclusion: Long sleep duration is associated with higher risk of CVD mortality among the elderly with poor sleep quality.
AB - Objective: To investigate the associations between sleep duration and mortality in the elderly by controlling for sleep quality. Method: Data were collected from participants in a cohort study in Shizuoka, Japan. A total of 14,001 elderly residents (aged 65-85 years), randomly chosen from all 74 municipalities in the prefecture, completed questionnaires that evaluated sleep duration, sleep complaints, and the use of hypnotics. Participants were followed from 1999 to 2006. We analyzed 11,395 subjects to estimate the hazard ratios (HR) for mortality from all causes and cardiovascular disease (CVD). Results: With 60,252 person-years, 1004 deaths were identified. While short sleep duration and mortality were not associated, longer sleep duration was associated with higher risk of mortality in both sexes. Compared with those who slept 7 h, the multivariate HR and 95% confidence interval of CVD mortality for those who slept ≥ 10 h was 1.95 (1.18-3.21) and, for those who slept ≤ 5 h, it was 1.10 (0.62-1.93). Although no clear association was found between sleep quality and mortality, long sleep duration was associated with higher risk of CVD mortality among those with poor sleep quality. Conclusion: Long sleep duration is associated with higher risk of CVD mortality among the elderly with poor sleep quality.
KW - Aged
KW - Cardiovascular diseases
KW - Cohort studies
KW - Sleep
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U2 - 10.1016/j.ypmed.2009.06.016
DO - 10.1016/j.ypmed.2009.06.016
M3 - Article
C2 - 19573557
AN - SCOPUS:70349298347
VL - 49
SP - 135
EP - 141
JO - Preventive Medicine
JF - Preventive Medicine
SN - 0091-7435
IS - 2-3
ER -
