Sjogren's syndrome with acute transverse myelopathy as the initial manifestation

Y. Manabe, C. Sasaki, H. Warita, T. Hayashi, Y. Shiro, K. Sakai, K. Kashihara, K. Abe

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

This is the first report of a patient with acute transverse myelopathy as the initial manifestation of primary Sjogren's syndrome (SS). The patient developed tetraparesis and sensory disturbance within 6 days of onset. Spinal MRI showed an extensive intraparenchymal lesion with high T2-weighted signal intensity, gadolinium enhancement, and cord swelling. Although the patient did not show clinical sicca symptoms, primary SS was diagnosed on the basis of clinical tests on lacrimal and salivary glands which showed high levels of autoantibodies. Treatment with prednisone improved motor and sensory symptoms and resulted in improvement of MRI findings. The present case suggests that acute transverse myelopathy can occur as an initial symptom of SS. (C) 2000 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)158-161
Number of pages4
JournalJournal of the neurological sciences
Volume176
Issue number2
DOIs
Publication statusPublished - Jun 15 2000

Keywords

  • Acute transverse myelopathy
  • Primary Sjogren's syndrome
  • Vasculitis

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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