Simultaneous Optical and Electrical Recording of Single Molecule Bonding to Single Channel Proteins

Toru Ide

doi:10.1002/cphc.201000560

Simultaneous Optical and Electrical Recording of Single Molecule Bonding to Single Channel Proteins

Toru Ide

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Two birds with one stone: A method is described for simultaneous optical and electrical recordings of single ion-channel proteins by combining the artificial bilayer technique and single-molecule imaging with a total internal reflection fluorescence microscope. Using this apparatus, interactions between single DNA molecules and single alpha-hemolysin channels are measured (see picture).

Original language	English
Pages (from-to)	3408-3411
Number of pages	4
Journal	ChemPhysChem
Volume	11
Issue number	16
DOIs	https://doi.org/10.1002/cphc.201000560
Publication status	Published - Nov 2010
Externally published	Yes

Keywords

DNA
Ion channels
Single-channel recording
Single-molecule studies
α-hemolysin

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Physical and Theoretical Chemistry

Access to Document

10.1002/cphc.201000560

Cite this

@article{b3b01e21cc1a4b83bcaa5229d39a4fe8,

title = "Simultaneous Optical and Electrical Recording of Single Molecule Bonding to Single Channel Proteins",

abstract = "Two birds with one stone: A method is described for simultaneous optical and electrical recordings of single ion-channel proteins by combining the artificial bilayer technique and single-molecule imaging with a total internal reflection fluorescence microscope. Using this apparatus, interactions between single DNA molecules and single alpha-hemolysin channels are measured (see picture).",

keywords = "DNA, Ion channels, Single-channel recording, Single-molecule studies, α-hemolysin",

author = "Toru Ide",

year = "2010",

month = nov,

doi = "10.1002/cphc.201000560",

language = "English",

volume = "11",

pages = "3408--3411",

journal = "ChemPhysChem",

issn = "1439-4235",

publisher = "Wiley-VCH Verlag",

number = "16",

}

TY - JOUR

T1 - Simultaneous Optical and Electrical Recording of Single Molecule Bonding to Single Channel Proteins

AU - Ide, Toru

PY - 2010/11

Y1 - 2010/11

N2 - Two birds with one stone: A method is described for simultaneous optical and electrical recordings of single ion-channel proteins by combining the artificial bilayer technique and single-molecule imaging with a total internal reflection fluorescence microscope. Using this apparatus, interactions between single DNA molecules and single alpha-hemolysin channels are measured (see picture).

AB - Two birds with one stone: A method is described for simultaneous optical and electrical recordings of single ion-channel proteins by combining the artificial bilayer technique and single-molecule imaging with a total internal reflection fluorescence microscope. Using this apparatus, interactions between single DNA molecules and single alpha-hemolysin channels are measured (see picture).

KW - DNA

KW - Ion channels

KW - Single-channel recording

KW - Single-molecule studies

KW - α-hemolysin

UR - http://www.scopus.com/inward/record.url?scp=78349232394&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78349232394&partnerID=8YFLogxK

U2 - 10.1002/cphc.201000560

DO - 10.1002/cphc.201000560

M3 - Article

C2 - 20830730

AN - SCOPUS:78349232394

SN - 1439-4235

VL - 11

SP - 3408

EP - 3411

JO - ChemPhysChem

JF - ChemPhysChem

IS - 16

ER -

Simultaneous Optical and Electrical Recording of Single Molecule Bonding to Single Channel Proteins

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this