Simultaneous functional group manipulation in the Meerwein-Ponndorf- Verley reduction process catalyzed by bidentate aluminum reagent

Takashi Ooi, Yoshifumi Itagaki, Tomoya Miura, Keiji Maruoka

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

Simultaneous reduction/oxidation sequence of hydroxy carbonyl substrates through Meerwein-Ponndorf-Verley reduction can be facilitated in the presence of bidentate aluminum catalyst, (2,7-dimethyl-1,8- biphenylenedioxy)bis(dimethylaluminum). This new approach provides the opportunity for efficient hydride transfer between two remotely situated functional groups.

Original languageEnglish
Pages (from-to)2137-2138
Number of pages2
JournalTetrahedron Letters
Volume40
Issue number11
DOIs
Publication statusPublished - Mar 12 1999
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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