Simple and sensitive headspace gas chromatographic determination of urinary methanol by means of syringe equilibration

Shigeru Suna, Nobuyuki Miyatake, Noriko Sakano, Takeshi Suzue, Fumiyuki Asakawa, Fumihiko Jitsunari, Tomohiro Hirao

Research output: Contribution to journalArticle

Abstract

Simple and sensitive headspace gas-chromatographic (GC) analysis of urinary methanol using syringe equilibration method was developed. A glass syringe containing 30 μL of urine sample and 50 mg of glass wool was heated at 85 °C for 20 minutes and the HS vapor equilibrated under normal pressure in the syringe was injected directly into the GC-FID, and the analysis was carried out successfully without contamination. Relative standard deviations of less than 5 % were observed for 20-80 μg/mL methanol spiked urine samples. The quantitative detection limit for urinary methanol was 0.3 μg/mL.

Original languageEnglish
Pages (from-to)865-868
Number of pages4
JournalBunseki Kagaku
Volume60
Issue number11
DOIs
Publication statusPublished - 2011
Externally publishedYes

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Syringes
Methanol
Gases
Glass
Wool
Gas chromatography
Contamination
Vapors

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Simple and sensitive headspace gas chromatographic determination of urinary methanol by means of syringe equilibration. / Suna, Shigeru; Miyatake, Nobuyuki; Sakano, Noriko; Suzue, Takeshi; Asakawa, Fumiyuki; Jitsunari, Fumihiko; Hirao, Tomohiro.

In: Bunseki Kagaku, Vol. 60, No. 11, 2011, p. 865-868.

Research output: Contribution to journalArticle

Suna, S, Miyatake, N, Sakano, N, Suzue, T, Asakawa, F, Jitsunari, F & Hirao, T 2011, 'Simple and sensitive headspace gas chromatographic determination of urinary methanol by means of syringe equilibration', Bunseki Kagaku, vol. 60, no. 11, pp. 865-868. https://doi.org/10.2116/bunsekikagaku.60.865
Suna, Shigeru ; Miyatake, Nobuyuki ; Sakano, Noriko ; Suzue, Takeshi ; Asakawa, Fumiyuki ; Jitsunari, Fumihiko ; Hirao, Tomohiro. / Simple and sensitive headspace gas chromatographic determination of urinary methanol by means of syringe equilibration. In: Bunseki Kagaku. 2011 ; Vol. 60, No. 11. pp. 865-868.
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