Significant effect of acyl groups on enantioselectivity in lipase-catalyzed transesterifications

Tadashi Ema, Soichi Maeno, Yusuke Takaya, Takashi Sakai, Masanori Utaka

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)


The effect of the acyl group of acylating agents on the enantioselectivity in the lipase-catalyzed transesterification of racemic 2-[(N,N-dimethylcarbamoyl)methyl]-3-cyclopenten-1-ol in diisopropyl ether was found to be significant. The enantioselectivity was enhanced markedly by changing the acylating agent from vinyl acetate to vinyl butyrate, and dropped substantially with longer acyl donors. Other acyl donors were also examined.

Original languageEnglish
Pages (from-to)625-628
Number of pages4
JournalTetrahedron Asymmetry
Issue number3
Publication statusPublished - Mar 21 1996

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry


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