Severe falciparum malaria with prolonged hemolytic anemia after successful treatment with intravenous artesunate

Ichiro Itoda, Takeshi Yasunami, Ken Kikuchi, Hisashi Yamaura, Kyoichi Totsuka, Kentaro Yoshinaga, Masanao Teramura, Hideaki Mizoguchi, Toshimitsu Hatabu, Shigeyuki Kano

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

We report a 68-year-old woman with severe falciparum malaria contracted in Tanzania. She presented high parasitemia and was treated successfully with intravenous artesunate, a qinghaosu derivative, and aggressive supportive therapy. She developed hemolytic anemia and jaundice on day 11 and blood transfusion was required. This case illustrates that intravenous artesunate has excellent antimalarial activity with rapid efficacy and that no severe adverse effect but conventional aggressive supportive therapy is still important in the treatment of severe falciparum malaria.

Original languageEnglish
Pages (from-to)600-603
Number of pages4
JournalKansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases
Volume76
Issue number8
Publication statusPublished - 2002
Externally publishedYes

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Falciparum Malaria
Hemolytic Anemia
Tanzania
Parasitemia
Antimalarials
Jaundice
Blood Transfusion
Therapeutics
artesunate

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Severe falciparum malaria with prolonged hemolytic anemia after successful treatment with intravenous artesunate. / Itoda, Ichiro; Yasunami, Takeshi; Kikuchi, Ken; Yamaura, Hisashi; Totsuka, Kyoichi; Yoshinaga, Kentaro; Teramura, Masanao; Mizoguchi, Hideaki; Hatabu, Toshimitsu; Kano, Shigeyuki.

In: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, Vol. 76, No. 8, 2002, p. 600-603.

Research output: Contribution to journalArticle

Itoda, I, Yasunami, T, Kikuchi, K, Yamaura, H, Totsuka, K, Yoshinaga, K, Teramura, M, Mizoguchi, H, Hatabu, T & Kano, S 2002, 'Severe falciparum malaria with prolonged hemolytic anemia after successful treatment with intravenous artesunate', Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, vol. 76, no. 8, pp. 600-603.
Itoda, Ichiro ; Yasunami, Takeshi ; Kikuchi, Ken ; Yamaura, Hisashi ; Totsuka, Kyoichi ; Yoshinaga, Kentaro ; Teramura, Masanao ; Mizoguchi, Hideaki ; Hatabu, Toshimitsu ; Kano, Shigeyuki. / Severe falciparum malaria with prolonged hemolytic anemia after successful treatment with intravenous artesunate. In: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 2002 ; Vol. 76, No. 8. pp. 600-603.
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AU - Yoshinaga, Kentaro

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