TY - JOUR
T1 - Serum total cholesterol of new students enrolled at Okayama University
T2 - Trend during 1989-1998
AU - Ogura, Toshio
AU - Matsuura, Kazuharu
AU - Suzuki, Hisao
AU - Kishida, Masayuki
AU - Ikeda, Satoru
AU - Tsukamoto, Chiaki
AU - Imai, Ayumi
AU - Tobe, Kazuo
PY - 2001/12/1
Y1 - 2001/12/1
N2 - To clarify the trend of hypercholesterolemia in Japanese adolescents, we investigated the serial changes in body mass index (BMI) and serum total cholesterol (TC) concentrations among 5,700 new students enrolled at Okayama University in 1989, 1993, and 1998. After confirming the stability of the TC assay of serum samples stored at -80°C, we measured serum TC levels in stored serum samples using an automated assay system. Although serum TC levels were higher in females than in males, these levels correlated weakly and positively with BMI (r = 0.21, P < 0.001) in males but not in females. Serum TC concentrations progressively increased from 1989-1998 in both sexes, irrespective of changes in BMI. In subjects with normal BMI (≥19 and <23 kg/m2), a significant increase in serum TC was noted from 1989-1998 in both males (157.2±1.0 to 163.6±0.9 mg/dl) and females (172.0±1.1 to 175.6±1.0 mg/dl). Our results indicate on increased incidence of hypercholesterolemia even in nonobese young Japanese adolescents. A concerted effort by health and education officials together with parents is necessary to prevent a further rise in the incidence of hypercholesterolemia among young Japanese.
AB - To clarify the trend of hypercholesterolemia in Japanese adolescents, we investigated the serial changes in body mass index (BMI) and serum total cholesterol (TC) concentrations among 5,700 new students enrolled at Okayama University in 1989, 1993, and 1998. After confirming the stability of the TC assay of serum samples stored at -80°C, we measured serum TC levels in stored serum samples using an automated assay system. Although serum TC levels were higher in females than in males, these levels correlated weakly and positively with BMI (r = 0.21, P < 0.001) in males but not in females. Serum TC concentrations progressively increased from 1989-1998 in both sexes, irrespective of changes in BMI. In subjects with normal BMI (≥19 and <23 kg/m2), a significant increase in serum TC was noted from 1989-1998 in both males (157.2±1.0 to 163.6±0.9 mg/dl) and females (172.0±1.1 to 175.6±1.0 mg/dl). Our results indicate on increased incidence of hypercholesterolemia even in nonobese young Japanese adolescents. A concerted effort by health and education officials together with parents is necessary to prevent a further rise in the incidence of hypercholesterolemia among young Japanese.
KW - Adolescent
KW - Body mass index
KW - Lifestyle-related disease
KW - Masked obesity
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M3 - Article
C2 - 11688949
AN - SCOPUS:0035491225
VL - 55
SP - 269
EP - 276
JO - Acta Medica Okayama
JF - Acta Medica Okayama
SN - 0386-300X
IS - 5
ER -