Abstract
Purpose: To explore the role of human herpesvirus-8 (HHV-8) in the pathogenesis of uveitis and other forms of ocular inflammation. Methods: Serum antibody titers to HHV-8 were measured in 76 patients with uveitis from various causes and other types of ocular inflammation in either the acute phase, the convalescent phase, or both. Results: Only one 21-year-old male patient in the convalescent phase of unilateral pars planitis showed a positive titer for HHV-8. His serum was negative for human immunodeficiency virus-1. Conclusions: Although the seropositive rate in the patient population was higher than that in the general population, the increased incidence was not statistically significant. The role of HHV-8 in the pathogenesis of intraocular inflammation appears to be limited.
| Original language | English |
|---|---|
| Pages (from-to) | 197-199 |
| Number of pages | 3 |
| Journal | Ocular Immunology and Inflammation |
| Volume | 10 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Sep 2002 |
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Keywords
- Antibody titer
- Human herpesvirus-8 (HHV-8)
- Ocular inflammation
- Uveitis
ASJC Scopus subject areas
- Ophthalmology
- Immunology and Allergy
Cite this
Seropositivity of human herpesvirus-8 in patients with uveitis. / Matsuo, Toshihiko; Itami, Masako.
In: Ocular Immunology and Inflammation, Vol. 10, No. 3, 09.2002, p. 197-199.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Seropositivity of human herpesvirus-8 in patients with uveitis
AU - Matsuo, Toshihiko
AU - Itami, Masako
PY - 2002/9
Y1 - 2002/9
N2 - Purpose: To explore the role of human herpesvirus-8 (HHV-8) in the pathogenesis of uveitis and other forms of ocular inflammation. Methods: Serum antibody titers to HHV-8 were measured in 76 patients with uveitis from various causes and other types of ocular inflammation in either the acute phase, the convalescent phase, or both. Results: Only one 21-year-old male patient in the convalescent phase of unilateral pars planitis showed a positive titer for HHV-8. His serum was negative for human immunodeficiency virus-1. Conclusions: Although the seropositive rate in the patient population was higher than that in the general population, the increased incidence was not statistically significant. The role of HHV-8 in the pathogenesis of intraocular inflammation appears to be limited.
AB - Purpose: To explore the role of human herpesvirus-8 (HHV-8) in the pathogenesis of uveitis and other forms of ocular inflammation. Methods: Serum antibody titers to HHV-8 were measured in 76 patients with uveitis from various causes and other types of ocular inflammation in either the acute phase, the convalescent phase, or both. Results: Only one 21-year-old male patient in the convalescent phase of unilateral pars planitis showed a positive titer for HHV-8. His serum was negative for human immunodeficiency virus-1. Conclusions: Although the seropositive rate in the patient population was higher than that in the general population, the increased incidence was not statistically significant. The role of HHV-8 in the pathogenesis of intraocular inflammation appears to be limited.
KW - Antibody titer
KW - Human herpesvirus-8 (HHV-8)
KW - Ocular inflammation
KW - Uveitis
UR - http://www.scopus.com/inward/record.url?scp=0037561544&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037561544&partnerID=8YFLogxK
U2 - 10.1076/ocii.10.3.197.15602
DO - 10.1076/ocii.10.3.197.15602
M3 - Article
VL - 10
SP - 197
EP - 199
JO - Ocular Immunology and Inflammation
JF - Ocular Immunology and Inflammation
SN - 0927-3948
IS - 3
ER -