Selectively substituted thiophenes and indoles by a tandem palladium-catalyzed multicomponent reaction

Koichi Mitsudo; Praew Thansandote; Thorsten Wilhelm; Brian Mariampillai; Mark Lautens

doi:10.1021/ol061373t

Selectively substituted thiophenes and indoles by a tandem palladium-catalyzed multicomponent reaction

Koichi Mitsudo, Praew Thansandote, Thorsten Wilhelm, Brian Mariampillai, Mark Lautens

Research output: Contribution to journal › Article › peer-review

67 Citations (Scopus)

Abstract

A variety of di- and trisubstituted thiophenes were synthesized by a one-pot palladium-catalyzed ortho-alkylation sequence terminated by either Heck or C-H coupling. Initial results toward the functionalization of indoles are also presented.

Original language	English
Pages (from-to)	3939-3942
Number of pages	4
Journal	Organic Letters
Volume	8
Issue number	18
DOIs	https://doi.org/10.1021/ol061373t
Publication status	Published - Aug 31 2006
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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title = "Selectively substituted thiophenes and indoles by a tandem palladium-catalyzed multicomponent reaction",

abstract = "A variety of di- and trisubstituted thiophenes were synthesized by a one-pot palladium-catalyzed ortho-alkylation sequence terminated by either Heck or C-H coupling. Initial results toward the functionalization of indoles are also presented.",

author = "Koichi Mitsudo and Praew Thansandote and Thorsten Wilhelm and Brian Mariampillai and Mark Lautens",

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AU - Thansandote, Praew

AU - Wilhelm, Thorsten

AU - Mariampillai, Brian

AU - Lautens, Mark

PY - 2006/8/31

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