Abstract
The synthesis of a series of gem- and vic-diborylated vinylsilanes was accomplished via highly selective transition-metal-catalyzed syn-dimetalation to the alkynylmetal species. This protocol served as a general synthetic method toward regio- and stereodefined multisubstituted olefins. The key steps are the diastereoselective Suzuki-Miyaura cross-coupling reactions of gem- and vic-diborylated vinylsilanes, in which the two boron groups showed discrete reactivities to afford diverse precursors of multisubstituted olefins.
Original language | English |
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Pages (from-to) | 285-295 |
Number of pages | 11 |
Journal | Journal of Organic Chemistry |
Volume | 79 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jan 3 2014 |
ASJC Scopus subject areas
- Organic Chemistry