Selective cleavage of primary MPM ethers with TMSI/Et3N

Isao Kadota, Yuji Yamagami, Naoya Fujita, Hiroyoshi Takamura

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A useful method for the selective cleavage of primary MPM ethers by using TMSI/Et3N is described. Other protective groups such as secondary MPM ethers, silyl ethers, and benzylidene acetal were stable under the reaction conditions.

Original languageEnglish
Pages (from-to)4552-4553
Number of pages2
JournalTetrahedron Letters
Volume50
Issue number31
DOIs
Publication statusPublished - Aug 5 2009

Keywords

  • Deprotection
  • MPM ether
  • Selective cleavage
  • TMSI

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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