Abstract
The combination of hydrogen azide with amines has proven to effect the C-2 opening of 2,3-epoxyester with high regioselectivity uniformly for trans-epoxyesters and depending on their structures for cis-2,3-epoxyesters.
| Original language | English |
|---|---|
| Pages (from-to) | 667-670 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 32 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Jan 28 1991 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
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Saito, S., Takahashi, N., Ishikawa, T., & Moriwake, T. (1991). Selective C-2 opening of 2,3-epoxyesters with HN3-amine system: A viable route to β-hydroxy-α-amino acids. Tetrahedron Letters, 32(5), 667-670. https://doi.org/10.1016/S0040-4039(00)74855-6