Selective C-2 opening of 2,3-epoxyesters with HN3-amine system: A viable route to β-hydroxy-α-amino acids

Seiki Saito; Nobuyosi Takahashi; Teruhiko Ishikawa; Toshio Moriwake

doi:10.1016/S0040-4039(00)74855-6

Selective C-2 opening of 2,3-epoxyesters with HN₃-amine system: A viable route to β-hydroxy-α-amino acids

Seiki Saito, Nobuyosi Takahashi, Teruhiko Ishikawa, Toshio Moriwake

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

The combination of hydrogen azide with amines has proven to effect the C-2 opening of 2,3-epoxyester with high regioselectivity uniformly for trans-epoxyesters and depending on their structures for cis-2,3-epoxyesters.

Original language	English
Pages (from-to)	667-670
Number of pages	4
Journal	Tetrahedron Letters
Volume	32
Issue number	5
DOIs	https://doi.org/10.1016/S0040-4039(00)74855-6
Publication status	Published - Jan 28 1991

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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abstract = "The combination of hydrogen azide with amines has proven to effect the C-2 opening of 2,3-epoxyester with high regioselectivity uniformly for trans-epoxyesters and depending on their structures for cis-2,3-epoxyesters.",

author = "Seiki Saito and Nobuyosi Takahashi and Teruhiko Ishikawa and Toshio Moriwake",

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AU - Moriwake, Toshio

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