Selective C-2 opening of 2,3-epoxyesters with HN3-amine system: A viable route to β-hydroxy-α-amino acids

Seiki Saito, Nobuyosi Takahashi, Teruhiko Ishikawa, Toshio Moriwake

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

The combination of hydrogen azide with amines has proven to effect the C-2 opening of 2,3-epoxyester with high regioselectivity uniformly for trans-epoxyesters and depending on their structures for cis-2,3-epoxyesters.

Original languageEnglish
Pages (from-to)667-670
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number5
DOIs
Publication statusPublished - Jan 28 1991

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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