Secretory Pattern of Inhibin During Estrous Cycle and Pregnancy in African (Loxodonta africana) and Asian (Elephas maximus) Elephants

Yuki Yamamoto, Natsuki Yuto, Tatsuya Yamamoto, Saroch Kaewmanee, Osamu Shiina, Yasushi Mouri, Etsuo Narushima, Masayuki Katayanagi, Keisuke Sugimura, Kentaro Nagaoka, Gen Watanabe, Kazuyoshi Taya

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The ovary of female elephants has multiple corpora lutea (CL) during the estrous cycle and gestation. The previous reports clearly demonstrated that inhibin was secreted from lutein cells as well as granulosa cells of antral follicles in cyclic Asian elephants. The aim of this study is to investigate the inhibin secretion during the pregnancy in African and Asian elephants. Two African elephants and two Asian elephants were subjected to this study. Circulating levels of immunoreactive (ir-) inhibin and progesterone were measured by radioimmunoassay. Four pregnant periods of an African elephant and three pregnant periods of an Asian elephant were analyzed in this study. Circulating levels of ir-inhibin started to increase at 1 or 2 week before the ovulation and reached the peak level 3 or 4 weeks earlier than progesterone during the estrous cycle in both African and Asian elephants. After last luteal phase, the serum levels of ir-inhibin remained low throughout pregnancy in both an African and an Asian elephant. The mean levels of ir-inhibin during the pregnancy were lower than the luteal phase in the estrous cycle despite high progesterone levels were maintained throughout the pregnancy. These results strongly suggest that CL secrete a large amount of progesterone but not inhibin during the pregnancy in elephants.

Original languageEnglish
Pages (from-to)511-522
Number of pages12
JournalZoo Biology
Volume31
Issue number5
DOIs
Publication statusPublished - Sep 2012
Externally publishedYes

Fingerprint

Elephas maximus
inhibin
Loxodonta africana
Elephantidae
estrous cycle
pregnancy
corpus luteum
progesterone
granulosa cells
radioimmunoassays
lutein
ovulation
secretion

Keywords

  • Corpus luteum
  • Estrous cycle
  • Female elephant
  • Inhibin
  • Pregnancy

ASJC Scopus subject areas

  • Animal Science and Zoology

Cite this

Secretory Pattern of Inhibin During Estrous Cycle and Pregnancy in African (Loxodonta africana) and Asian (Elephas maximus) Elephants. / Yamamoto, Yuki; Yuto, Natsuki; Yamamoto, Tatsuya; Kaewmanee, Saroch; Shiina, Osamu; Mouri, Yasushi; Narushima, Etsuo; Katayanagi, Masayuki; Sugimura, Keisuke; Nagaoka, Kentaro; Watanabe, Gen; Taya, Kazuyoshi.

In: Zoo Biology, Vol. 31, No. 5, 09.2012, p. 511-522.

Research output: Contribution to journalArticle

Yamamoto, Y, Yuto, N, Yamamoto, T, Kaewmanee, S, Shiina, O, Mouri, Y, Narushima, E, Katayanagi, M, Sugimura, K, Nagaoka, K, Watanabe, G & Taya, K 2012, 'Secretory Pattern of Inhibin During Estrous Cycle and Pregnancy in African (Loxodonta africana) and Asian (Elephas maximus) Elephants', Zoo Biology, vol. 31, no. 5, pp. 511-522. https://doi.org/10.1002/zoo.20415
Yamamoto, Yuki ; Yuto, Natsuki ; Yamamoto, Tatsuya ; Kaewmanee, Saroch ; Shiina, Osamu ; Mouri, Yasushi ; Narushima, Etsuo ; Katayanagi, Masayuki ; Sugimura, Keisuke ; Nagaoka, Kentaro ; Watanabe, Gen ; Taya, Kazuyoshi. / Secretory Pattern of Inhibin During Estrous Cycle and Pregnancy in African (Loxodonta africana) and Asian (Elephas maximus) Elephants. In: Zoo Biology. 2012 ; Vol. 31, No. 5. pp. 511-522.
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