Secondary sclerosing cholangitis and portal hypertension after O157 enterocolitis: Extremely rare complications of hemolytic uremic syndrome

Naoto Urushihara, Norifumi Ariki, Takanori Oyama, Yasuhiro Chouda, Takahito Yagi, Takuya Inoue, Yoshie Tomiyama, Ritsuo Nishiuchi, Megumi Oda, Noriaki Tanaka

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The authors experienced an extremely rare case of secondary sclerosing cholangitis and portal hypertension developed as late complications of hemolytic uremic syndrome (HUS) owing to Escherichia coli O157:H7 in a 2-year-old boy. HUS after E coli O157 infection is the most frequent cause of acute renal failure in childhood and occasionally is accompanied by extrarenal complications such as encephalopathy, cardiomyopathy, ischemic colitis, and pancreatitis. Rarely, late colonic stenosis may develop secondary to the ischemic damage. Sclerosing cholangitis and subsequent cirrhosis with portal hypertension are very uncommon as late complications of HUS. To our knowledge, such a case has not been previously reported in the literature.

Original languageEnglish
Pages (from-to)1838-1840
Number of pages3
JournalJournal of Pediatric Surgery
Volume36
Issue number12
DOIs
Publication statusPublished - Dec 2001

Keywords

  • Escherichia coli O157:H7
  • Hemolytic uremic syndrome
  • Portal hypertension
  • Sclerosing cholangitis

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health

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