We observe adhesion sites of a cell on a substrate with high resolution. Since this observation requires interfacial measurements between the cell and the substrate, we employ scanning localized surface plasmon microscopy. We experimentally show that focal adhesion sites of a mouse muscle cell can be observed without fluorescent labeling. We also show that a non-scanning surface plasmon microscope combined with the scanning localized surface plasmon microscope contributes to observing an entire cell adhesion site and identify regions of interest.
|Number of pages||6|
|Journal||Biomedical Optics Express|
|Publication status||Published - Feb 1 2012|
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics