Satisfaction and subjective symptoms after instillation of tafluprost or travoprost for twelve weeks each

Tomomi Nakamura, Takashi Kanamoto, Naoki Komatsu, Masaki Tanito, Shinichiro Teranishi, Tomoko Naito, Tetsuya Baba, Kazuyuki Hirooka, Shiro Mizoue, Yoshiaki Kiuchi

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Purpose : To report satisfaction and subjective symptoms after instillation of tafluprost followed by travoprost, or vice versa, for 12 weeks each. Cases and Method : This prospective study was made by 29 institutions including 7 universities. We evaluated 174 eyes of 174 cases after eliminating 21 eyes out of 195 cases. The series comprised 71 males and 103 females. The age ranged from 38 to 94 years, average 70 years. There were 167 cases of primary open-angle glaucoma and 7 cases of ocular hypertension. The cases were randomly divided into 2 groups. One group received instillation of 0.0015% tafluprost for 2 weeks and then instillation of 0.004% travoprost for 2 weeks. The other group received travoprost followed by travoprost for 2 weeks each. Satisfaction and subjective symptoms were evaluated by questionnaire. Results : There was no difference in subjective symptoms between tafluprost and travoprost. Tafluprost was significantly preferred over travoprost regarding satisfaction, presumably due to difference in the shape of commercially available ophthalmic solution. Conclusion : No difference was present between tafluprost and travoprost regarding subjective symptoms. Tafluprost was favored by the majority of patients.

Original languageEnglish
Pages (from-to)959-966
Number of pages8
JournalJapanese Journal of Clinical Ophthalmology
Issue number7
Publication statusPublished - Jul 2014

ASJC Scopus subject areas

  • Ophthalmology


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